Results 31 to 40 of about 331,710 (264)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi +5 more
wiley +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye +33 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Plasma Freezing Quality under Action of Magnetic Field
Zhileng xuebao, 2022 In this study, the efficient preservation of fresh frozen plasma was investigated. Improving the quick freezing efficiency was achieved by adding a magnetic field to assist the freezing process. The changes in plasma ice crystal structure and size in the
Lan Hui +5 more
doaj
The Effect of Hybrid Drying Methods on the Quality of Dried Carrot
Applied Sciences, 2022 The study investigated the effect of a combination of drying techniques: convection, microwave, and freeze-drying, on selected physical properties of the dried material (carrot) to determine which form of hybrid drying is the best alternative to ...
Agnieszka Ciurzyńska +5 more
doaj +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Microalbumin and Freezing [PDF]
Clinical Chemistry, 1997 “Microalbumin” (MA; albumin present in very small quantities) has assumed an increased role in the early diagnosis, assessment, and treatment of diabetic kidney disease (1)(2)(3)(4)(5). The measurement is reliably carried out by several methods, but the practical issue of MA stability during urine storage for extended periods remains controversial. MA
V T, Innanen, B M, Groom, F M, de Campos
openaire +2 more sources
Physical Review D, 2023 15 pages, 6 figures + 1 secret doodle, comments ...
Saniya Heeba +2 more
openaire +2 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source