Results 111 to 120 of about 989,743 (383)

Freezing of living cells: mechanisms and implications.

open access: yesAmerican Journal of Physiology, 1984
Cells can endure storage at low temperatures such as--196 degrees C for centuries. The challenge is to determine how they can survive both the cooling to such temperatures and the subsequent return to physiological conditions.
P. Mazur
semanticscholar   +1 more source

THE FREEZING OF INSECTS [PDF]

open access: yesThe Canadian Entomologist, 1898
In the 22nd Report of the Entomological Society of Ontario, being that for 1891, there appeared a paper from my pen under the title “Can Insects Survive Freezing?”I have recently come across further records of observations upon this subject, and deem them of sufficient interest to be republished in the Canadian Entomologist.In looking over and ...
openaire   +3 more sources

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Activation of Periodate by Freezing for the Degradation of Aqueous Organic Pollutants.

open access: yesEnvironmental Science and Technology, 2018
A new strategy (i.e., freezing) for the activation of IO4- for the degradation of aqueous organic pollutants was developed and investigated. Although the degradation of furfuryl alcohol (FFA) by IO4- was negligible in water at 25 °C, it proceeded rapidly
Yejin Choi   +6 more
semanticscholar   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

open access: yesMolecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti   +10 more
wiley   +1 more source

Cereal grains and glycerol in Agaricus blazei cryopreservation

open access: yesBioscience Journal, 2013
Agaricus blazei é um basidiomiceto de importância comercial amplamente estudado quanto à sua atividade biológica. Entretanto, pouco foi estudado sobre as técnicas de preservação deste basidiomiceto, sendo a criopreservação uma alternativa.
Henrique Susumu Tanaka   +4 more
doaj  

Freezing tolerance and survival experiments with various intertidal organisms from Kachemak Bay, Alaska [PDF]

open access: yes, 2004
Thesis (M.S.) University of Alaska Fairbanks, 2004Intertidal organisms at high latitudes experience multiple stresses created by freezing, including ischemia, free water reduction, and distortion and destruction of cells, and in response have adapted ...
Patterson, Heather Kristine
core  

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Influence of Freezing and Storage Procedure on Human Urine Samples in NMR-Based Metabolomics

open access: yesMetabolites, 2013
It is consensus in the metabolomics community that standardized protocols should be followed for sample handling, storage and analysis, as it is of utmost importance to maintain constant measurement conditions to identify subtle biological differences ...
Burkhard Luy   +6 more
doaj   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

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