Results 201 to 210 of about 257,814 (269)

Optogenetic LTP Manipulation and Mathematical Modeling to Investigate Value Plasticity of the Instructive Signal in Mice. [PDF]

Bio Protoc
Nagashima T, Higashino I, Arima-Yoshida F, Hiyoshi K, Nagase M, Yada Y, Naoki H, Watabe AM.   +7 more
europepmc   +1 more source

Gardiquimod Nanoemulsion Targets Cutaneous Leishmaniasis Lesions Reducing Systemic Toxicity and Parasite Burden

Advanced Healthcare Materials, EarlyView.
Nanoemulsion delivery of a TLR7 agonist enhances safety and promotes colocalization with Leishmania‐infected macrophages in skin lesions, enabling a ∼2‐log reduction in parasite burden. However, tissue‐level constraints and TLR‐driven regulatory feedback generate a mixed immune response that limits complete parasite clearance.
Carmen Palomino‐Cano, M. Carmen Mera‐Delgado, Esther Moreno, Esther Larrea, Lecnia Aguirre, Jonathan Miguel Zanatta, Sónia Barros‐Carvalho, Iola F. Duarte, Ricardo Silvestre, Juan M. Irache, Javier Carrión, Socorro Espuelas   +11 more
wiley   +1 more source

Advancing human ovarian biology in tandem with clinical care: considerations for collecting ovarian tissue for research after oophorectomy for tissue cryopreservation. [PDF]

Front Endocrinol (Lausanne)
Brunette MA, Burns K, Hoefgen H, Xiao S, Duncan FE, Laronda MM, Shikanov A, Zelinski M, Gomez-Lobo V.   +8 more
europepmc   +1 more source

Temporal Immune and Metabolic Shifts Drive the Anti‐Tumor Efficacy of Resiquimod‐Loaded Nanoparticles in Peritoneal Carcinomatosis

Advanced Healthcare Materials, EarlyView.
Peritoneal carcinomatosis is a hard‐to‐treat spread of abdominal cancers that often returns after therapy. Nanoparticles were developed to retain an immune‐boosting drug in the abdomen. When combined with chemotherapy in mice, this approach eliminated tumors in many cases and prevented recurrence, helping the immune system mount a stronger, longer ...
Vanessa Chan, Po‐Han Chao, XuXin Sun, Jun Han, Sarah MacPherson, Lucas J. Andrew, Noah Y. Brittain, Tien Do, Marcel B. Bally, Julian J. Lum, Shyh‐Dar Li   +10 more
wiley   +1 more source

Study on tensile mechanical response and microstructure of polypropylene fiber reinforced loess under freezing. [PDF]

PLoS One
Wang Y, Liu C, Zhong Y, Mao E, He F.
europepmc   +1 more source

Sodium Alginate‐Based Submucosal Lifting Hydrogel for Endoscopic Mucosal Resection and Endoscopic Submucosal Dissection

Advanced Healthcare Materials, EarlyView.
A biocompatible sodium alginate‐based hydrogel is developed as a next‐generation submucosal lifting agent intended for EMR and ESD. The optimized formulation exhibits a composition devoid of endotoxins, high viscosity, demonstrates reliable injectability, and ensures prolonged mucosal elevation.
Iram Maqsood, Venkata S. Akshintala, Surya T. Evani, Rebecca A. Krimins, Yihan Wang, Keith Freel, Ahmed Ibrahim, Saowanee Ngamruengphong, Mouen Khashab, Stephen W. Hoag   +9 more
wiley   +1 more source

Research progress on cold tolerance key genes and mechanisms in four major northern China crops. [PDF]

Front Plant Sci
Liu G, Wang H, Tang Y, Gao H, Wang Y, Sun Y, Yu S, Zhang D.   +7 more
europepmc   +1 more source

Corticotropin-Releasing Factor and Somatostatin Neurons in the Central Amygdala Mediate Dynamic Defensive Behaviors during Fear Extinction. [PDF]

J Neurosci
Le QE, Lardant E, Siddiqui Y, Alam T, Evans K, Fadok JP.   +5 more
europepmc   +1 more source

Harmonic Control of Dynamical Freezing in Programmable Rydberg Atom Arrays

Ghosh R, Sarkar M, Zindorf B, Mukherjee B, Bose S.   +4 more
europepmc   +1 more source