Results 51 to 60 of about 2,098,494 (316)

Instrument and Means interpretation of deverbal nominals: The role of ambiguous stative verbs in French VN compounding

open access: yesZeitschrift für Wortbildung, 2020
This article examines French Verb-Noun compounds with Means value (couvre-pied 'blanket', lit. cover-feet), derived from stative bases. It shows that they are generally ambiguous between Means and Instrument reading.
Marie Laurence Knittel   +1 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Au service des langues et de leur enseignement : l’humaniste plurilingue Jacques Bourgoing

open access: yesContextes et Didactiques, 2018
While medieval intellectual circles valued no languages other than ancient, in the sixteenth century the advent of vernaculars on the linguistic scene started to reverse this balance of power.
Marie Cézard-Leyral
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

The Collection of Eighteenth-Century French Novels 1751–1800

open access: yesJournal of Open Humanities Data
The French Enlightenment is a pivotal period in European intellectual and literary history, which can be studied through this dataset of French novels first published between 1751 and 1800.
Julia Röttgermann
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

New Orleans, Nodal Point of the French Atlantic [PDF]

open access: yes, 2007
This article argues for the importance of New Orleans within French and Francophone Studies, with a particular emphasis on a French Atlantic perspective.
Marshall, Bill, Bill Marshall
core   +1 more source

ENGLISH IN THE ALGERIAN UNIVERSITY: DAILY PRACTICES, REPRESENTATION(S) AND LINGUISTIC ASPIRATION(S) [PDF]

open access: yesAnalele Universităţii din Craiova. Psihologie, Pedagogie
Our present study is in the form of a questionnaire survey, conducted among 200 students, enrolled in the Science & Technology and Biology departments during the 2023 academic year.
Aouda MAZOT, Chahrazed KHELFI
doaj   +1 more source

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