Results 71 to 80 of about 4,272,039 (309)

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

The high scope approach to early learning [PDF]

open access: yes, 2012
Learning Objectives: After studying this chapter the reader should be able to: • Describe the historical origins, the longitudinal research, and the theoretical underpinnings of the HighScope approach.
French, Geraldine
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Peter and Paul: Images of Pair Personages by Linguistic Data (on Material of English, French and Russian Languages)

open access: yesНаучный диалог, 2018
The phraseological material of the English and French languages that includes appellative derivatives from personal names Peter ( Pierre ) and Paul is considered.
D. M. Golikova
doaj   +1 more source

First-year students’ communication apprehension in learning French as foreign language

open access: yesIndonesian Journal of Applied Linguistics, 2020
Learning a foreign language and being first-year students at the same time can be challenging as they struggle to make the transition in learning a new language and adjusting to their new lives as a university student. Students have to deal with not only
Dante Darmawangsa   +2 more
doaj   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

The Visit of General Washington to Newport in 1781 [PDF]

open access: yes, 1913
A paper read before the Society December 17th, 1912 by Mrs. French E. Chadwick. Bulletin of the Newport Historical Society, Number Six (extra number), Newport, R.I., February, 1913.
Chadwick, French E.
core   +1 more source

Gain Bounds for Multiple Model Switched Adaptive Control of General MIMO LTI Systems

open access: yes, 2008
For the class of MIMO minimal LTI systems controlled by an estimation based multiple model switched adaptive controller (EMMSAC), bounds are obtained for the closed loop lp gain, 1 ? p ?
Buchstaller, Dominic, French, Mark
core   +1 more source

Vous or tu? Native and non-native speakers of French on a sociolinguistic tightrope [PDF]

open access: yes, 2004
Sociolinguistic rules governing choice of pronouns of address are notoriously difficult in French, despite the fact that the number of variants is rather limited: the more formal vous versus the more informal tu.
Dewaele, Jean-Marc
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

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