Results 41 to 50 of about 10,373 (113)

Scientific knowledge about dementia: From the Global South to the world

Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract Most people with dementia live in low‐ and middle‐income countries (LMICs), but scientific knowledge about dementia is dominated by Global North perspectives. This interdisciplinary article combines expertise from Latin America, India, and Europe, using a mixed‐methodology approach that incorporates expert discussions, a narrative review, and ...
Timothy Daly, Ignacio López‐Barrenechea, Paulina Vergara, Faheem Arshad, Avanthi Paplikar, Aparajita Ray Chaudhuri, Lucía Crivelli, Agustín Ibáñez, Suvarna Alladi, Andrea Slachevsky   +9 more
wiley   +1 more source

Tau PET and multimodal brain imaging in patients at risk for chronic traumatic encephalopathy. [PDF]

, 2019
ObjectiveTo characterize individual and group-level neuroimaging findings in patients at risk for Chronic Traumatic Encephalopathy (CTE).MethodsEleven male patients meeting criteria for Traumatic Encephalopathy Syndrome (TES, median age: 64) underwent ...
Baker, Suzanne L, Bourakova, Viktoriya, Chaudhary, Kiran, Edwards, Lauren, Gardner, Raquel C, Jagust, William J, Janabi, Mustafa, Kramer, Joel H, La Joie, Renaud, Lesman-Segev, Orit H, Miller, Bruce L, O'Neil, James P, Perry, David C, Rabinovici, Gil D, Sonni, Ida, Stephens, Melanie L, Tsai, Richard, Visani, Adrienne V   +17 more
core  

Progress in Huntington's disease: the search for markers of disease onset and progression. [PDF]

, 2015
Unlike most neurodegenerative disorders, individuals at risk from Huntington's disease can be identified prior to the onset of clinical signs of the disease by virtue of it being an autosomal dominant condition. This provides the hypothetical opportunity
Barker, Roger A, Mason, Sarah
core   +1 more source

The landscape of dementia research, diagnosis, treatment, and care in Latin America

Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract Latin America is undergoing rapid population aging alongside a rising burden of dementia. While the region holds substantial potential for dementia risk reduction, challenges remain, such as delayed diagnoses, limited access to specialized care and biomarker testing, persistent stigma, and deep‐rooted structural inequities.
Claudia K. Suemoto, Nilton Custodio, Diego Aguilar, José A. Avila‐Funes, Sandra Baez, Pablo M. Bagnati, Lisa L. Barnes, Sonia M. D. Brucki, Ismael L. Calandri, Paulo Caramelli, Mario Cornejo‐Olivas, Carolina Delgado Derio, Sergio T. Ferreira, Adolfo M. García, Lea T. Grinberg, Agustin M. Ibanez, Rosario Isasi, Sylvia E. Josephy‐Hernández, Maria Lazo Porras, Jorge J. Llibre‐Guerra, Juan J. Llibre‐Rodriguez, Mychael V. Lourenco, B. Marcela Mar Meza, Joaquin Migeot, J. Jaime Miranda, Claudia Miranda‐Castillo, Catherine J. Mummery, José F. Parodi, Natalia Pozo Castro, Rosa María Salinas Contreras, Hernando Santamaría‐García, Andrea Slachevsky, Juliana N. Souza‐Talarico, Ezequiel I. Surace, Leonel T. Takada, Elena Tsoy, Martha Unaucho Pilalumbo, Eduardo R. Zimmer, Igor C Fontana, Simin Mahinrad, Heather M. Snyder, Maria C. Carrillo   +41 more
wiley   +1 more source

CHARACTERISTICS OF INDIVIDUALS UNDERGOING PANEL GENETIC TESTING FOR PRIMARY BRAIN TUMORS [PDF]

, 2018
Background. Currently, there are no genetic testing guidelines for patients with a primary brain tumor (PBT). This population is largely understudied in terms of the family history, tumor grade, pathology, and their relation to genetic contribution.
Azam, Sarah
core   +1 more source

Efficacy of vinblastine in central nervous system Langerhans cell histiocytosis: a nationwide retrospective study [PDF]

, 2011
Background Vinblastine (VBL) is the standard treatment for systemic Langerhans cell histiocytosis (LCH), but little is known about its efficacy in central nervous system (CNS) mass lesions. Methods
Sophie Ng Wing Tin, Nadine Martin-Duverneuil, Ahmed Idbaih, Catherine Garel, Maria Ribeiro, Judith Parker, Anne-Sophie Defachelles, Anne Lambilliotte, Mohamed Barkaoui, Martine Munzer, Martine Gardembas, Jean Sibilia, Patrick Lutz, Renato Fior, Michel Polak, Alain Robert, Olivier Aumaitre, Dominique Plantaz, Corinne Armari-Alla, Thierry Genereau, Perrine Berard, Ghislain Talom, Jean-Loup Pennaforte, Hubert Le Pointe, Marie-Anne Barthez, Gérard Couillault, Julien Haroche, Karima Mokhtari, Jean Donadieu, Khê Hoang-Xuan, null null   +30 more
core   +2 more sources

Frailty and Health Outcomes in People 65 Years or Older Living With Dementia: A Systematic Review of the Literature

Journal of the American Geriatrics Society, Volume 74, Issue 3, Page 854-867, March 2026.
ABSTRACT Introduction Although frailty is considered a potentially modifiable risk factor for dementia, its influence on health outcomes in individuals with established dementia remains unclear. This study aims to systematize the current evidence to understand the impact of frailty on the development of adverse outcomes in older adults with dementia ...
Miguel German Borda, Luis Carlos Venegas‐Sanabria, Marco Canevelli, Francesco Landi, Salomón Páez‐García, Kevin O'Hara‐Veintimilla, Lindsay Wallace, Kenneth Rockwood, Tommy Cederholm, Gustavo Duque, Mario Ulises Pérez‐Zepeda, Dag Aarsland   +11 more
wiley   +1 more source

Epilepsy, hippocampal sclerosis and febrile seizures linked by common genetic variation around SCN1A [PDF]

, 2013
Epilepsy comprises several syndromes, amongst the most common being mesial temporal lobe epilepsy with hippocampal sclerosis. Seizures in mesial temporal lobe epilepsy with hippocampal sclerosis are typically drug-resistant, and mesial temporal lobe ...
Alhusaini, S, Becker, A, Becker, F, Berkovic, SF, Blumcke, I, Buchfelder, M, Buono, RJ, Catarino, CB, Cavalleri, GL, Chaves, J, Coras, R, Costa, PP, da Silva, AM, Dahl, HH, de Graan, PN, Delanty, N, Depondt, C, Doherty, CP, Dorn, T, Duncan, S, Eriksson, KJ, Gruber-Sedlmayr, U, Hakonarson, H, Hallmann, K, Hamer, HM, Hansen, J, Hessel, EV, Hildebrand, MS, Kantanen, AM, Kasperaviciute, D, Kobow, K, Koeleman, BP, Krämer, G, Kunz, WS, Kälviäinen, RK, Leal, B, Lerche, H, Leu, C, Matarin, M, Meng Tan, K, Novy, J, O'Brien, TJ, Pandolfo, M, Paravidino, R, Petrovski, S, Ramasamy, A, Reif, PS, Reinthaler, EM, Robbiano, A, Rosenow, F, Ryten, M, Rössler, K, Scheffer, IE, Schlachter, K, Schoch, S, Silva, BM, Sisodiya, SM, Smith, C, Sperling, MR, Steinhoff, BJ, Stogmann, E, Striano, P, Théâtre, E, Tostevin, A, Trabzuni, D, UK Brain Expression Consortium, The, von Lehe, M, Weale, ME, Weber, Y, Zara, F, Zimprich, F, Zumsteg, D   +71 more
core   +1 more source

Enhanced hippocampal long-term potentiation and spatial learning in aged 11ß-hydroxysteroid dehydrogenase type 1 knock-out mice [PDF]

, 2007
Glucocorticoids are pivotal in the maintenance of memory and cognitive functions as well as other essential physiological processes including energy metabolism, stress responses, and cell proliferation.
Brownstein, D., Cobb, S., Hibberd, C., Mcnair, Kara, Morris, R.G.M., Morton, N., Mullins, J.J., Noble, J., Seckl, J.R., Yau, J.L.W.   +9 more
core   +2 more sources

Air pollution, a rising environmental risk factor for cognition, neuroinflammation and neurodegeneration: The clinical impact on children and beyond

, 2016
International audienceAir pollution (indoors and outdoors) is a major issue in public health as epidemiological studies have highlighted its numerous detrimental health consequences (notably, respiratory and cardiovascular pathological conditions).
Calderón-Garcidueñas, L., Heydarpour, P., Leray, Emmanuelle, Reis, J, Torres-Jardón, R.   +4 more
core   +3 more sources