Results 81 to 90 of about 1,328,641 (294)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Rotating black hole orbit functionals in the frequency domain

open access: yes, 2003
In many astrophysical problems, it is important to understand the behavior of functions that come from rotating (Kerr) black hole orbits. It can be particularly useful to work with the frequency domain representation of those functions, in order to bring
C. Cutler   +19 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Wideband Channel Estimation and Prediction in Single-Carrier Wireless Systems

open access: yes, 2005
—In this contribution wideband channel estimation and prediction designed for single-carrier wideband wireless communications systems are investigated. Specifically, the single-carrier wideband pilot signal received by the receiver is first converted to ...
Hanzo, L., Liu, W., Yang, L-L.
core  

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Adaptive SVD Denoising in Time Domain and Frequency Domain

open access: yesApplied Sciences
In seismic data processing, noise not only affects velocity analysis and seismic migration, but also causes potential risks in post-stack processing because of the artifacts.
Meixuan Ren   +5 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Frequency Domain Image Filtering Using CUDA [PDF]

open access: yesMehran University Research Journal of Engineering and Technology, 2014
In this paper, we investigate the implementation of image filtering in frequency domain using NVIDIA?s CUDA (Compute Unified Device Architecture). In contrast to signal and image filtering in spatial domain which uses convolution operations and hence is ...
Muhammad Awais Rajput   +2 more
doaj  

Unraveling quantum dissipation in the frequency domain

open access: yes, 1998
We present a quantum Monte Carlo method for solving the evolution of an open quantum system. In our approach, the density operator evolution is unraveled in the frequency domain.
A. Barchielli   +12 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

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