Results 91 to 100 of about 2,451,313 (284)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Piecewise Volterra modelling of the Duffing oscillator in the frequency domain [PDF]
, 2010 When analysing the nonlinear Duffing oscillator, the weak nonlinearity is basically dependent on the amplitude range of the input excitation. The nonlinear differential equation models of such nonlinear oscillators, which can be transformed into the ...
Billings, S.A., Li, L.M.
core
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Dynamic Tests on a Concrete Slab with a Tuned Mass Damper
MATEC Web of Conferences, 2015 Nowadays, structures became more slender and flexible due to lighter materials with great resistance, compared to traditional materials used in construction. This fact provides to structural systems with low natural frequencies. High amplitude vibrations
Campuzano Carmona Jorge Eliécer +2 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Frequency Domain Analysis of Lossy and Non-Uniform Twisted Wire Pair
IEEE Access, 2019 In the study of the frequency domain crosstalk for twisted pair, the traditional alternating inversion model is often built under the ideal condition of lossless and uniform media, ignoring the length of the twisted section.
Yaxiu Sun +3 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Comprehensive bearing condition monitoring algorithm for incipient fault detection using acoustic emission [PDF]
Jurnal Tribologi, 2014 The bearing reliability plays major role in obtaining the desired performance of any machine. A continuous condition monitoring of machine is required in certain applications where failure of machine leads to loss of production, human safety and ...
Amit R. Bhende +2 more
doaj
Analysis of a duffing oscillator that exhibits hysteresis with varying excitation frequency and amplitude [PDF]
, 2007 Hysteresis, or jump phenomenon, are a common and severe nonlinear behaviour associated with the Duffing oscillator and the multi-valued properties of the response solution.
Billings, S.A., Li, L.M.
core +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source