Results 131 to 140 of about 5,871,149 (318)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
IET Radar, Sonar & NavigationRadar systems are evolving towards distributed receiver networks. As individual stations might be separated too far to install a cable link, novel methods are required to synchronise individual data records in the time domain.
Erik Busley +3 more
doaj +1 more source
Materials Today AdvancesRecent developments in the engineering of metallic glasses (MGs) with custom properties have been compelling, particularly in porous constructions.
Junsheng Liu +6 more
doaj +1 more source
Frequency standards based on laser-manipulated atoms in ions Proceedings
, 1996 The following topics were dealt with: optical frequency standards, atomic frequency standards, molecular frequency standards, laser cooled atoms, trapped ions, atomic clocks, passive frequency standards, Ramsey experiments, laser frequency stabilityy ...
Penselin, S. (eds.) +2 more
core
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
MetrologyThis paper introduces a method for calibrating radar sensors in a multi-sensor cinemometer system using a reference cinemometer based on CW Doppler radar. The method involves synchronizing sensors, pairing data with reference measurements, and performing
Seif Ben-Hassine +4 more
doaj +1 more source
Frequency Invariant Beamforming in Subbands
, 2004 In this paper, two subband implementations of a frequency invariant beamformer (FIB) are studied. In the first structure, the received array signals are split into subbands and an FIB is operated in each of the corresponding decimated subbands, with a ...
Weiss, S, Liu, Wei, Liu, W, Weiss, S.
core +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source