Results 151 to 160 of about 313,545 (301)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

"Monitoring the Coupling-Update Frequency"

open access: yes, 2021
In operational applications lateral-boundary coupling data are provided to one-way nested limited-area models with time intervals of more than an order of magnitude larger than the time step of the coupled model.
Termonia, P.
core  

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Calculation of normal mode spectra in laterally heterogeneous earth models using an iterative direct solution method,

open access: yes
Normal mode observations play an important role in studying broad-scale lateral variations in the Earth. Such studies require the calculation of accurate synthetic spectra in realistic earth models, and this remains a computationally challenging problem.
Deuss, Arwen   +2 more
core   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Dynamic response of vehicle-track coupling system with an insulated rail joint

open access: yes, 2013
The dynamic behavior of vehicle and track systems is studied in the presence of an insulated rail joint through a two-dimensional vehicle-track coupling model.
Grossoni, Ilaria   +3 more
core  

Working Memory and Cross-Frequency Coupling of Neuronal Oscillations. [PDF]

open access: yesFront Psychol, 2021
Abubaker M, Al Qasem W, Kvašňák E.
europepmc   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

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