Results 61 to 70 of about 5,461,422 (271)
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Research on the Deception Mechanism of Frequency Diverse Array Radar in Radar Reconnaissance and Direction Finding [PDF]
Hangkong bingqiIn the ground attack mission, the attack plan needs to be formulated and distributed to the attack aircraft based on the threat source intelligence data obtained in advance with the help of the tactical mission planning system.
Zhang Jing, Wang Bo, Meng Guoxiang, Chen Shuangyan
doaj +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
A MISO Frequency Diverse Array Implementation [PDF]
, 2023 The separation of RF signals from different angles of arrival is a key objective for a radarreceiver. A common approach to spatial separation relies on the measurement of a linear phaseprogression across multiple receive antenna elements, where the rate ...
Kellerman, Nicholas
core +1 more source
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Designing Planar Frequency Diverse Arrays in Space-Frequency Domain
, 2022 Abstract Antenna arrays benefit from spatial diversity, which allows controlling the pattern specifications in space. Adding frequency diversity to the arrays initiates opportunity to control the beams in the Space-Time domain. Frequency Diverse Array (FDA) has a Range-Angle dependent pattern; therefore, the array's spatial and time behavior ...
Maryam Hasheminasab +2 more
openaire +1 more source
IWO-based Synthesis of Log-Periodic Dipole Array [PDF]
The Invasive Weed Optimization (IWO) is an effective evolutionary and recently developed method. Due to its better performance in comparison to other well-known optimization methods, IWO has been chosen to solve many complex non-linear problems in ...
Lazaridis, Pavlos
core +3 more sources