Results 91 to 100 of about 2,177,340 (291)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
SensorsBased on the energy equation of the hemispherical resonator, this study analyzes the influence of ion beam balancing on the frequency split of the hemispherical resonator.
Boran Li, Changhong Wang, Zhen Fang
doaj +1 more source
Low-frequency fluctuations in the Lang-Kobayashi equations
Physical Review E, 2003 The Lang-Kobayashi equations are simplified by a local analysis that focuses, in the long-delay-time limit, on one pair of mode-antimode only. In the domain of hysteresis between the two steady states, low frequency fluctuations (LFF) can be observed if there is a domain of bistability where both steady states are unstable.
Pieroux, Didier, Mandel, Paul
openaire +3 more sources
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Jixie chuandong, 2014 Based on Lagrange equation,the vibration equation of the belt drive mechanism with strongly nonlinear is established.By means of the method of L-P,the primary resonance of the belt drive mechanism system with strongly nonlinear is analyzed.The amplitude ...
李高峰
doaj
Advances in Civil EngineeringThe traditional equation of impact echo (IE) thickness resonant frequency upon P-wave reflections is developed based on P-wave velocity and thickness of the plate and a geometric correction factor.
Yujin Wang +8 more
doaj +1 more source
Low frequency acoustic and electromagnetic scattering [PDF]
This paper deals with two classes of problems arising from acoustics and electromagnetics scattering in the low frequency stations. The first class of problem is solving Helmholtz equation with Dirichlet boundary conditions on an arbitrary two ...
Hariharan, S. I., Maccamy, R. C.
core +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
A new principle technic for the transformation from frequency domain to time domain
AIP Advances, 2017 A principle technic for the transformation from frequency domain to time domain is presented. Firstly, a special type of frequency domain transcendental equation is obtained for an expected frequency domain parameter which is a rational or irrational ...
Ben-Qing Gao
doaj +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source