Results 81 to 90 of about 2,195,899 (341)

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Pair creation and plasma oscillations [PDF]

open access: yes, 2000
We describe aspects of particle creation in strong fields using a quantum kinetic equation with a relaxation-time approximation to the collision term.
Hecht, M. B.   +4 more
core   +3 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Rotatory vibration of sphere of higher order viscoelastic solid

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1994
An attempt is made to investigate the rotatory vibration of a sphere of higher order viscoelastic solid considering higher order strain rate and stress rate. The general frequency equation is obtained for this type of vibration of a sphere.
P. R. Sengupta   +3 more
doaj   +1 more source

The Excited of Electromagnetic Waves for Langmuir Waves in Relativistic Plasma

open access: yesIbn Al-Haitham Journal for Pure and Applied Sciences, 2005
The study of the excited nonlinear Langmuir waves has been obtained in relativistic plasma in a resonance beat frequency for two high frequency laser waves.
A. S.Wahdain , J. A. Hassan
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Frequency Unifying Equation

open access: yes
Here I unify frequency across the domains, using Venus...as my guide...sounds crazy...it works..I DID IT!!!!! Yayayayayay I actually did it!!!! Yay me!!
openaire   +4 more sources

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