Results 51 to 60 of about 377,227 (256)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

THE PHASE REACTOR INDUCTANCE SELECTION TECHNIQUE FOR POWER ACTIVE FILTER

Electrical engineering & Electromechanics, 2016
Purpose. The goal is to develop technique of the phase inductance power reactors selection for parallel active filter based on the account both low-frequency and high-frequency components of the electromagnetic processes in a power circuit.
D. V. Tugay
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

A New Software-Defined Vehicular Radio Communications System Based on DS-CDMA Technology Using Orthogonal Walsh-Hadamard Codes

IEEE Access
This paper presents a new software-defined vehicular radio communication system based on the DS-CDMA technology using orthogonal Walsh-Hadamard codes. The proposed radio communication system can simultaneously receive an audio stereo signal and a data ...
Radu Gabriel Bozomitu, Marian Alexandru Corban, Stefan Corneliu Stoica   +2 more
doaj   +1 more source

Left auditory cortex is involved in pairwise comparisons of the direction of frequency modulated tones

Frontiers in Neuroscience, 2013
Evaluating series of complex sounds like those in speech and music requires sequential comparisons to extract task-relevant relations between subsequent sounds.
Nicole eAngenstein, André eBrechmann
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Unveiling the Extremely Low Frequency Component of Heart Rate Variability

Applied Sciences
Heart rate variability (HRV) comprises several components driven by various internal processes, the least understood of which is the ultra-low frequency (ULF) one. Recently published research has shown that the HRV frequency distribution in this range is
Krzysztof Adamczyk, Adam G. Polak
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Semiconductor loss calculation of DC–DC modular multilevel converter for HVDC interconnections

High Voltage, 2018
DC–DC modular multilevel converter (DC–DC MMC) is an attractive candidate for high-voltage DC (HVDC) interconnections since it can provide the required voltage matching, galvanic isolation and flexible power control abilities.
Shanshan Zhao, Yu Chen, Li Peng
doaj   +1 more source