Results 21 to 30 of about 5,206,901 (306)
Millimeter-wave monolithic diode-grid frequency multiplier [PDF]
A semiconductor diode structure useful for harmonic generation of millimeter or submillimeter wave radiation from a fundamental input wave is fabricated on a GaAs substrate.
Maserjian, Joseph
core +1 more source
A terahertz grid frequency doubler [PDF]
We present a 144-element terahertz quasi-optical grid frequency doubler. The grid is a planar structure with bow-tie antennas as a unit cell, each loaded with a planar Schottky diode.
Alina Moussessian +7 more
core +2 more sources
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Phase detector circuit synthesizes own reference signal [PDF]
Circuit with isolation amplifier connected to a frequency multiplier and synchronous phase detector synthesizes the phase reference signal from the phase modulated input ...
core +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Very Low Power Cockcroft-Walton Voltage Multiplier for RF Energy Harvesting Applications [PDF]
A device was required that could harvest the electromagnetic energy present in ambient radio frequency (RF) signals. A part of this device must convert the AC RF signal received by the antenna into a DC signal that can be used in an embedded application.
Langdon, Trace
core +2 more sources
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins
We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó +7 more
wiley +1 more source
Interior feedback stabilization of wave equations with dynamic boundary delay [PDF]
In this paper we consider an interior stabilization problem for the wave equation with dynamic boundary delay.We prove some stability results under the choice of damping operator.
Ammari, Kaïs, Gerbi, Stéphane
core +4 more sources
A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley +1 more source

