Results 111 to 120 of about 1,755,884 (316)

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Peak-to-average Power Ratio of Orthogonal Frequency Division Multiplexing

, 2002
Orthogonal frequency division multiplexing (OFDM) is successfully used in many wireless digital communication systems over multipath channels. One of the principal disadvantages of OFDM is the occurrence of high peak to average power ratios (PAR). Many
Jayalath, Dhammika, Tellambura, Chintha
core  

Assessing landslide susceptibility in Lake Abya catchment, Rift Valley, Ethiopia: A GIS-based frequency ratio analysis

Journal of Degraded and Mining Lands Management
Ethiopia's varied landscape, significant rainfall, and diverse geological characteristics pose risks of landslides. The specific research area spans 40 km2 within the Lake Abaya catchment area in the Rift Valley of Ethiopia.
Yonas Oyda, Muralitharan Jothimani, Hailu Regasa   +2 more
doaj   +1 more source

On the distribution of frequency ratios of kHz QPOs

, 2009
Accepted for publication in MNRAS, 9 pages, 9 ...
Boutelier, Martin, Barret, Didier, Lin, Yongfeng, Torok, Gabriel   +3 more
openaire   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Modified U Slot Patch Antenna with Large Frequency Ratio for Vehicle-to-Vehicle Communication. [PDF]

Sensors (Basel), 2023
Govindarajulu SR, Tarek MNA, Guerra MR, Hassan A, Alwan E.   +4 more
europepmc   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Supercapacitor assisted LDO (SCALDO) techniquean extra low frequency design approach to high efficiency DC-DC converters and how it compares with the classical switched capacitor converters

, 2013
Supercapacitor assisted low dropout regulators (SCALDO) were proposed as an alternative design approach to DC-DC converters, where the supercapacitor circulation frequency (switching frequency) is in the order of few Hz to few 10s of Hz, with an output ...
Nihal Kulatana, Kankanamge, Kosala, Kularatna, Nihal, Kosala Kankanmage, Kulatana, Nihal, Kankanmage, Kosala   +5 more
core   +1 more source

A study on multiple-model evaluation of landslide susceptibility

Carsologica Sinica
Landslides are one of the most common geological disasters in China, characterized by sudden occurrence and uncertainty. The evaluation of landslide susceptibility is a complex process.
Cheng HUANG, Yunlong DENG, Xiangsheng YAN, Xincheng ZHOU   +3 more
doaj   +1 more source

A multiband SSr diode RF rectifier with an improved frequency ratio for biomedical wireless applications. [PDF]

Sci Rep, 2023
Muhammad S, Waly MI, AlJarallah NA, Ghayoula R, Negm AS, Smida A, Iqbal A, Tiang JJ, Roslee M.   +8 more
europepmc   +1 more source