Results 31 to 40 of about 4,597,743 (231)

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

open access: yesMolecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

KALMAN FILTERING FOR SPACE-TIME CODED TRANSMISSIONS OVER FREQUENCY-SELECTIVE RAYLEIGH FADING CHANNELS

open access: yesElectrica, 2005
The problem of multichannel estimation for space-time coded transmissions over frequency-selective Rayleigh fading channels is addressed. Under  fast fading conditions, receivers employing Kalman filtering and moderate complexity equalization schemes are
Ahmet Korhan TANÇ, Reyat YILMAZ
doaj   +2 more sources

Iterative Decoding of Serial Concatenated Convolutionally Encoded Signals over Frequency Selective Fading Channels

open access: yesJournal of Engineering and Sustainable Development, 2007
Serial concatenated convolutional coding with iterative decoding is examined for data transmission employing BFSK (binary frequency shift keying) modulation and non-coherent detection receiver.
Maha George Zia
doaj  

New OSTBC for Blind Channel Estimation and Tracking in MIMO-OFDM Systems

open access: yesJournal of Telecommunications and Information Technology, 2019
Applying orthogonal space time block coding (OSTBC) to multiple-input multiple-output (MIMO) systems helps reduce receiver complexity. However, this approach has been applied only to flat fading channels, as when the channel is a frequency selective ...
Abdelkader Tami   +2 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Channel and delay estimation for base-station-based cooperative communications in frequency-selective fading channels

open access: yesSouth African Journal of Science, 2011
A channel and delay estimation algorithm for both positive and negative delay, based on the distributed Alamouti scheme, has been recently discussed for base-station-based asynchronous cooperative systems in frequency-flat fading channels.
Hongjun Xu, Laneil Padayachee
doaj  

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Performance of Fractionally Spread Multicarrier CDMA in AWGN as Well as Slow and Fast Nakagami-m Fading Channels

open access: yes, 2005
—In multicarrier code-division multiple-access (MCCDMA), the total system bandwidth is divided into a number of subbands, where each subband may use direct-sequence (DS) spreading and each subband signal is transmitted using a subcarrier frequency.
Yang, L-L., Hanzo, L.
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

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