Results 91 to 100 of about 4,794,485 (241)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Application of a modified fou rier transformation for modeling variations in the gravity field

open access: yesИзвестия высших учебных заведений: Геология и разведка
Introduction. The analysis and processing of signals with complex structures — particularly those exhibiting frequency and phase modulation — remains a relevant challenge, especially in cases where traditional methods fail to provide sufficient accuracy.
R. R. Nigmatullin   +3 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

FREQUENCY DOMAIN TRANSFORM AND THE COULOSTATIC TECHNIQUE

open access: yesCorrosion Reviews, 1998
Abstract Using linear system principles and network analysis, a unique characteristic of the charge transfer occurring in the usage of the Coulostatic method was evaluated. It was found that such transfer to the electrochemical corrosion cell approximates a current impulse, and that the cell voltage response in the time domain to that ...
R. Alvarez, M. Sanchez
openaire   +1 more source

Transformation of Rhizoctonia solani [PDF]

open access: yes, 2003
The aim of this study was to develop a genetic transformation system for the plant pathogenic fungus Rhizoctonia solani (teliomorph, Thanatephprus cucumeris Frank [Donk]). The availability of a transformation system would allow us to study gene exchange,
Wu, Jiang
core  

Amplitude-frequency characteristic of the transformation ratio of the 35-kV CVT.

open access: yes, 2018
Amplitude-frequency characteristic of the transformation ratio of the 35-kV CVT.
Jian Le (2832722)   +3 more
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Frequency of spontaneous neoplastic transformation in bystander cells.

open access: yes, 2013
Neoplastic transformation frequency in the progeny of bystander C3H 10T½ MEFs assayed 10 population doublings after they had been in co-culture with 1 GeV/nucleon iron ion- or sham-irradiated MEFs.
Manuela Buonanno (349029)   +2 more
core   +1 more source

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