Results 71 to 80 of about 4,794,485 (241)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Edam: An Efficient Clique Discovery Algorithm
, 2006 this paper, we propose an efficient algorithm, EDAM, for finding motifs based on frequency transformation and Minimum Bounding Rectangle (MBR ...
With Frequency Transformation +4 more
core
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
A new principle technic for the transformation from frequency domain to time domain
AIP Advances, 2017 A principle technic for the transformation from frequency domain to time domain is presented. Firstly, a special type of frequency domain transcendental equation is obtained for an expected frequency domain parameter which is a rational or irrational ...
Ben-Qing Gao
doaj +1 more source
Robust Time-Frequency Watermarking Based on Improved S Transformation
, 2011 In this paper, a robust image watermarking method with one-dimensional improved S transformation is proposed which is robust against geometric distortion. This watermarking is detected by a linear frequency change.
Qing Shuang Zeng +2 more
core +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Вплив інгібітору тирозинових протеїнкіназ геністеїну на агробактеріальну трасформацію рослин
Фактори експериментальної еволюції організмів, 2015 Aims. Agrobacterium-mediated method of DNA transfer allows to introduce in plant a big genetic construction with minimum effect on transferable gene sequence, and also it does not require special equipment. The interaction between plant and agrobacterium
В. Федорчук, А. І. Ємець
doaj
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Characterization of a Come3 Homologue Essential for DNA Transformation in Helicobacter Pylori
, 2009 To find genes involved in natural competence in Helicobacter pylori, we used a bioinformatics database search and found two transformation-related open reading frames (ORFs): a comE3 homologue (HP1361 ORF) of Bacillus subtilis and a comL homologue ...
YEH, YU-CHING;CHANG, KAI-CHIH;WANG, JIN-TOWN +1 more
core