Results 71 to 80 of about 1,623,042 (284)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
浙江大学学报. 农业与生命科学版, 2007 To explore the transformation efficiency on cultivated wheat with gene expression cassette lacking vector backbone sequences, transformation of wheat cultivars by biolistic bombardment with bar gene expression cassette was proceeded through isolating ...
SHI Nong-nong +3 more
doaj +1 more source
TARRAGON (Artemisia dracunculus L.) “HAIRY” ROOT CULTURE PRODUCTION [PDF]
Biotechnologia Acta, 2016 This paper is devoted the biotechnology development of Artemisia dracunculus L. genetic transformation. We obtained the transgenic A. dracunculus “hairy” root culture using A. rhizogenes A4-mediated transformation.
K. O. , А. М. , N. A.
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
A new principle technic for the transformation from frequency domain to time domain
AIP Advances, 2017 A principle technic for the transformation from frequency domain to time domain is presented. Firstly, a special type of frequency domain transcendental equation is obtained for an expected frequency domain parameter which is a rational or irrational ...
Ben-Qing Gao
doaj +1 more source
Vibrational Features of Water at the Low-Density/High-Density Liquid Structural Transformations
, 2011 A structural transformation in water upon compression was recently observed at the temperature $T=277$~K in the vicinity of the pressure $p \approx 2\;000$~Atm [R.M. Khusnutdinoff, A.V. Mokshin, J. Non-Cryst. Solids \textbf{357}, 1677 (2011)].
Allen +43 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Optimization of digital filters performances simultaneously in frequency and time domains
Российский технологический журнал, 2020 Wide used method of digital filters design consists in transformation of analog filter-prototype with required performances into digital filter. This method is applicable if the transformation preserves optimality of filter performances under specified ...
A. V. Smirnov
doaj +1 more source