Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Influence of GGBS and Mono Steel Fiber on Strength Characteristics of Self-Compacting Concrete [PDF]
E3S Web of ConferencesIn recent scenarios, self-compacting concrete (SCC) has played a vital role in the construction industry. In the fresh state, SCC has flow ability, passing ability, and filling ability. SCC also had better strength and durability properties. The addition
Revanth S. +8 more
doaj +1 more source
Tests of properties of fresh concrete
Magazine of Concrete Research, 1952 Summary A description is given of a deformability meter for studying the properties of fresh concrete which has been evolved at the Swedish Cement and Concrete Research Institute. Examples are adduced to demonstrate the effects produced by varying mixes and by the admixture of resins. The test results afford information on the tendency to segregation
openaire +3 more sources
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Evaluation of the Fresh Properties of Cement Pastes: Part I-Response Models Applied to Changes in the One-Variable-at-a-Time Method. [PDF]
Materials (Basel), 2023 Maia L.
europepmc +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Composite binders for concretes with improved shock resistance
Инженерно-строительный журнал, 2019 The qualitative and quantitative composition and properties of the initial materials, composite binders and concrete samples were studied. Optimal compositions of concrete for protective structures that provide the maximum static and dynamic strength ...
Roman Fediuk +6 more
doaj +1 more source
Effect of Cement Type and Water-to-Cement Ratio on Fresh Properties of Superabsorbent Polymer-Modified Cement Paste. [PDF]
Materials (Basel), 2023 Dilbas H.
europepmc +1 more source
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
Application of Artificial Intelligence to Evaluate the Fresh Properties of Self-Consolidating Concrete. [PDF]
Materials (Basel), 2021 Feng Y +4 more
europepmc +1 more source