Results 71 to 80 of about 187,266 (192)

Visualizing mitochondrial FoF1-ATP synthase as the target of the immunomodulatory drug Bz-423

, 2018
Targeting the mitochondrial enzyme FoF1-ATP synthase and modulating its catalytic activities with small molecules is a promising new approach for treatment of autoimmune diseases. The immuno-modulatory compound Bz-423 is such a drug that binds to subunit
Börsch, Michael, Glick, Gary D., Starke, Ilka   +2 more
core   +1 more source

Metabolic FRET sensors in intact organs: Applying spectral unmixing to acquire reliable signals

Biology Open, 2023
Lautaro Gándara, Lucía Durrieu, Pablo Wappner   +2 more
doaj   +1 more source

Progress and Prospects in FRET for the Investigation of Protein–Protein Interactions

Biosensors
Protein–protein interactions (PPIs) play a crucial role in various biological processes, including signal transduction, transcriptional regulation, and metabolic pathways.
Yue Zhang, Xinyue Ma, Meihua Zhu, Vivien Ya-Fan Wang, Jiajia Guo   +4 more
doaj   +1 more source

Single molecule studies on the dynamics of the transcription initiation complex of yeast mitochondria [PDF]

, 2017
Department of Biomedical EngineeringThe transcription initiation complex in the yeast mitochondria of Saccharomyces cerevisiae comprises the RNA polymerase, Rpo41, the initiation factor, Mtf1, and the DNA including 6 base pair promoter sequence. The Mtf1
Cho, Hayoon
core  

Biological applications of ternary quantum dots: A review

Nanotechnology Reviews, 2022
Aladesuyi Olanrewaju A., Lebepe Thabang C., Maluleke Rodney, Oluwafemi Oluwatobi S.   +3 more
doaj   +1 more source

From principles to practice: a comprehensive guide to FRET-FLIM in plants

Methods in Microscopy
Förster Resonance Energy Transfer combined with Fluorescence Lifetime Imaging Microscopy (FRET-FLIM) is revolutionizing plant biology, by enabling the study of protein–protein interactions (PPIs) within live cells.
Eljebbawi Ali, Dolata Anika, Strotmann Vivien I., Weidtkamp-Peters Stefanie, Stahl Yvonne   +4 more
doaj   +1 more source

Mining the Sinorhizobium meliloti transportome to develop FRET biosensors for sugars, dicarboxylates and cyclic polyols.

PLoS ONE, 2012
BackgroundFörster resonance energy transfer (FRET) biosensors are powerful tools to detect biologically important ligands in real time. Currently FRET bisosensors are available for twenty-two compounds distributed in eight classes of chemicals (two ...
Alexandre Bourdès, Steven Rudder, Alison K East, Philip S Poole   +3 more
doaj   +1 more source

Illuminating cell signaling with genetically encoded FRET biosensors in adult mouse cardiomyocytes. [PDF]

, 2018
FRET-based biosensor experiments in adult cardiomyocytes are a powerful way of dissecting the spatiotemporal dynamics of the complicated signaling networks that regulate cardiac health and disease. However, although much information has been gleaned from
Chen-Izu, Ye, Jaradeh, Mark, Jian, Zhong, Reddy, Gopireddy Raghavender, Shi, Qian, Wang, Ying, West, Toni M, Xiang, Yang K   +7 more
core  

Regulatory assembly of the vacuolar proton pump VOV1-ATPase in yeast cells by FLIM-FRET

, 2010
We investigate the reversible disassembly of VOV1-ATPase in life yeast cells by time resolved confocal FRET imaging. VOV1-ATPase in the vacuolar membrane pumps protons from the cytosol into the vacuole. VOV1-ATPase is a rotary biological nanomotor driven
Batisse, Claire, Boersch, Michael, Boettcher, Bettina, Ernst, Stefan, Zarrabi, Nawid   +4 more
core   +1 more source

Sensitive detection of p65 homodimers using red-shifted and fluorescent protein-based FRET couples.

PLoS ONE, 2007
BackgroundFluorescence Resonance Energy Transfer (FRET) between the green fluorescent protein (GFP) variants CFP and YFP is widely used for the detection of protein-protein interactions.
Joachim Goedhart, Joop E M Vermeer, Merel J W Adjobo-Hermans, Laura van Weeren, Theodorus W J Gadella   +4 more
doaj   +1 more source