Results 111 to 120 of about 77,925 (341)

The role of oxidation in the fretting wear process [PDF]

open access: yes
Fretting experiments were conducted on titanium, a series of Ni-Cr-Al alloys and on some high temperature turbine alloys at room temperature and at elevated temperatures in air and in various inert environments.
Bill, R. C.
core   +1 more source

The AUTACE That Degrades KRAS and Engages CD8+ T Cells for the Treatment of KRAS/TP53 Co‐Mutant Tumors

open access: yesAdvanced Science, EarlyView.
AUTACE is a bifunctional nanoplatform that integrates tumor targeting, immune engagement, and on‐demand KRAS degradation. It targets KRAS/TP53 co‐mutant tumors via TP53‐specific TCRs, elicits antitumor CD8+ T‐cell responses through surface anti‐CD3 antibodies, and uses low‐intensity focused ultrasound (LIFU) to trigger controlled release of the KRAS ...
Luo Li   +6 more
wiley   +1 more source

TRANSITION IN THE FRETTING PHENOMENON [PDF]

open access: yesFiabilitate şi Durabilitate, 2017
Fretting is now fully identified as a small amplitude oscillatory motion which induces a harmonic tangential force between two surfaces in contact. It is related to three main loadings, i.e.
Stefan Ghimisi
doaj  

Degradation of road tested automotive connectors

open access: yes, 2000
The automotive environment is particularly demanding on connector performance, and is characterized by large temperature changes, high humidity and corrosive atmospheres.
Maul, C., McBride, J.W., Swingler, J.
core   +1 more source

A model of fretting wear in the contact of an axisymmetric indenter and a visco-elastic half-space [PDF]

open access: yes, 2015
This article may be downloaded for personal use only. Any other use requires prior permission of the author and AIP Publishing. This article appeared in AIP Conference Proceedings 1683, 020040 (2015) and may be found at https://doi.org/10.1063/1.4932730 ...
Dimaki, Andrey V., Popov, Valentin L.
core   +1 more source

Endoplasmic Reticulum Geometry Dictates Neuronal Bursting via Calcium Store Refill Rates and Exposes Selective Neuronal Vulnerability

open access: yesAdvanced Science, EarlyView.
The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving
Valentina Davi   +13 more
wiley   +1 more source

Study on the Effect of Laser Quenching on Fretting Fatigue Life

open access: yesMetals, 2019
Laser quenching hardening is one of the most used surface treated technologies. In order to study the effect of laser quenching on the fretting fatigue life, fretting fatigue experiments of TC11 (Ti-6.5Al-1.5Zr-3.5Mo-0.3Si) titanium alloy specimens with ...
Hongjian Zhang   +3 more
doaj   +1 more source

On the mechanics of fretting fatigue

open access: yesWear, 1988
Abstract The current state of knowledge of the prediction of fretting fatigue is reviewed and a summary given of the way fracture mechanics may be used to analyse a propagating crack. Recent experimental work on an aluminium alloy, HE15-TF, which discovered a distinct size effect (indicating that the absolute size of the contact has a marked effect ...
Hills, D, Nowell, D, Oconnor, J
openaire   +1 more source

Mechanoadaptation via Myosin Cytoplasmic Redistribution Protects Circulating Tumor Cells From Shear‐induced Death During Hematogenous Dissemination

open access: yesAdvanced Science, EarlyView.
This study investigates how CTCs survive varying shear stress during hematogenous metastasis. We uncover a self‐protection mechanism, by which non‐adherent CTCs adapt to high shearing milieu through accumulated cytoplasmic myosin‐mediated disruption of myosin‐actin binding, attenuating force transmission into chromatin to protect CTCs from shear ...
Cunyu Zhang   +10 more
wiley   +1 more source

Tetrahedral DNA Nanostructure‐Based Biomimetic Nanovesicles Attenuate Sepsis‐Associated ARDS by Suppressing Glycolysis via the BMAL1/PFKFB3 Axis

open access: yesAdvanced Science, EarlyView.
Upon inhalation, RM@TNT could persist long‐term in the diseased lungs, while undergoing disintegration to release TNT specifically within the ROS‐rich pathological microenvironments of SA‐ARDS. The released TNT was then precisely delivered to AMs via Tuftsin, where it released Nob intracellularly to activate BMAL1 expression, thus inhibiting AM ...
Yunlong Zhang   +23 more
wiley   +1 more source

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