Results 101 to 110 of about 9,013 (298)
An Integrated DNA Nanoprobe for Intranuclear Imaging and in Situ Profiling of OGG1 Activity
Advanced Science, EarlyView.The TP‐SA nanoprobe, integrating an AS1411 aptamer for nuclear delivery and a FRET array for signal amplification, enables real‐time tracking of nuclear OGG1 activity. It reveals cell‐line‐specific basal OGG1 levels and shows clinical promise using pneumonia patients’ lavage fluid.
Mingzhu Zhao +9 more
wiley +1 more source
Fretting Wear and Corrosion in Liquid Lead-Bismuth Eutectic: A Review of Current State and Prospect
Engineered ScienceLead–bismuth eutectic (LBE) is a promising coolant for Generation-IV reactors. The corrosion of LBE and the fretting wear caused by fluid-induced vibration will gradually become the main causes of component failure.
Hui Chen +4 more
doaj +1 more source
Advanced Science, EarlyView.Eco‐friendly enzymatic synthesis of high‐fidelity, site‐specifically modified DNA using 3′‐blocked nucleotides for full synthetic control and next‐generation sequencing compatibility. ABSTRACT Methods for site‐specific incorporation of modified DNA building blocks remain limited.
Raveena Raveena +2 more
wiley +1 more source
, 2019 It is well established that damage to the first bodies in fretting wear gives rise to a hard and brittle tribologically transformed structure (TTS) which can influence both wear and fatigue.
Sun, Wei +3 more
core +1 more source
TRANSITION IN THE FRETTING PHENOMENON [PDF]
Fiabilitate şi Durabilitate, 2017 Fretting is now fully identified as a small amplitude oscillatory motion which induces a harmonic tangential force between two surfaces in contact. It is related to three main loadings, i.e.
Stefan Ghimisi
doaj
On the mechanics of fretting fatigue
Wear, 1988 Abstract The current state of knowledge of the prediction of fretting fatigue is reviewed and a summary given of the way fracture mechanics may be used to analyse a propagating crack. Recent experimental work on an aluminium alloy, HE15-TF, which discovered a distinct size effect (indicating that the absolute size of the contact has a marked effect ...
Hills, D, Nowell, D, Oconnor, J
openaire +1 more source
Advanced Science, EarlyView.Host‐specific compatibility between RNF138‐like proteins and flavivirus NS5 determines NS5 stability. Mammalian RNF138 but not arthropod homologs recognizes and induces conserved NS5/RdRp K48‐linked ubiquitination and proteasomal degradation, thereby restricting viral replication. Ectopic RNF138 in mice attenuates TBEV‐induced pathogenesis. (Created in
Jialiang Sun +6 more
wiley +1 more source
The evaluation of wear in the fretting of electrical contact surfaces
, 2008 Consideration is given to methods for the evaluation of surface wear from fretted electrical contact surfaces. The surfaces under consideration are selected for in-vivo applications, they are testing using purpose built fretting apparatus to investigate ...
Cross, K.J., McBride, J.W.
core
AI‐Physics‐Experiment Trinity for Integrated Protein Dynamics Modeling
Advanced Science, EarlyView.This review unites experiments, physics‐based simulations, and AI as a synergistic triad for protein dynamics modeling. It highlights integrative strategies, resolves sampling and forcefield bottlenecks, and outlines challenges and future directions for accurate, interpretable conformational ensemble prediction.
Chen Shi +4 more
wiley +1 more source
Advanced Science, EarlyView.This study presents a surfaceome‐reprogramming strategy for mutation‐independent lung cancer therapy by repurposing dexamethasone to prime mesenchymal stem cell‐derived nanovesicles. The engineered vesicles leverage multi‐valent interactions mediated by upregulated adhesion proteins, EPHA2, and NOTCH3.
Geunhye Kim +8 more
wiley +1 more source