Results 51 to 60 of about 378,591 (316)
Experimental characterization of friction coefficients at the tool-chip-workpiece interface in cutting: Evaluation of lubrication efficiency of mineral oil [PDF]
, 2010 Collaboration avec le LTDS/ENISEThe characterization of friction coefficients at the tool-chip-workpiece interface remains an issue. This paper presents a new experimental set-up able to simulate similar tribological phenomena as the ones occurring at ...
RECH, Joël +4 more
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Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Demo 03-02 Static vs. Sliding Friction [PDF]
, 2001 This demonstration shows that the coefficient of static friction is greater than the coefficient of dynamic or sliding friction for the same two surfaces.
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An integrated approach to friction surfacing process optimisation [PDF]
, 2001 This paper discusses the procedures for data collection, management and optimisation of the friction surfacing process. Experimental set-up and characteristics of measuring equipment are found to match the requirements for accurate and unbiased data ...
V.I Vitanov +9 more
core +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Qualification of a robotized Friction Stir Welding System [PDF]
, 2010 This paper presents an experimental methodology to determine a Friction Stir Welding (FSW) means of production based on the experimental study of the tool / material mechanical interactions generated during the welding operation.
MARTIN, Patrick +5 more
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Multi-physics simulation of friction stir welding process [PDF]
, 2009 Purpose: The Friction Stir Welding (FSW) process comprises of several highly coupled (and non-linear) physical phenomena: large plastic deformation, material flow transportation, mechanical stirring of the tool, tool-workpiece surface interaction ...
Robert Hamilton +7 more
core +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Demo 03-05 Surface Dependence of Friction [PDF]
, 2001 This demonstration illustrates that the frictional force between different surfaces is very different. Four identical brass blocks are placed on strips of four different materials, and one end of the device is raised, as indicated in Figure 1, until ...
core
Energy and force analysis of linear friction welds in medium carbon steel [PDF]
, 2010 The linear friction welding process is rapidly developing into an important manufacturing technology for high quality joining of engineering materials.
Colegrove, Paul A. +7 more
core +1 more source