Results 61 to 70 of about 378,591 (316)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Shock isolation systems incorporating Coulomb friction [PDF]

, 2012
This study investigates a novel approach to the problem of shock isolation. The questions considered are whether friction produces a better performance in terms of reduced response during a shock compared to viscous damping and a lower residual response ...
Ismail, Mohd
core  

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Finite element modelling for temperature, stresses and strains calculation in linear friction welding of TB9 titanium alloy

Journal of Materials Research and Technology, 2019
In the present paper, finite element method (FEM) simulation of linear friction welding (LFW) TB9 titanium alloy was carried out using ABAQUS software.
Xiawei Yang, Wenya Li, Ying Fu, Qing Ye, Yaxin Xu, Xiurong Dong, Kaiwei Hu, Yangfan Zou   +7 more
doaj   +1 more source

Overview of the mean of production used for FSW [PDF]

, 2010
The Friction Stir welding process is now introduced in production plants. More and more applications are developed and the most part of the work is now centered on the mean of production to be used.
ZIMMER-CHEVRET, Sandra, LAYE, Julien, LANGLOIS, Laurent, BIGOT, Régis   +3 more
core  

Effect of tool centreline deviation on the mechanical properties of friction stir welded DH36 steel [PDF]

, 2015
Friction stir welding of steel has gone through recent tool and optimisation developments allowing the process to be considered as a technically superior alternative to fusion welding.
Cater, Stephen R., Galloway, Alexander, Toumpis, Athanasios, Tingey, Christopher   +3 more
core   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Interfacial microstructure evolution and formation process of the joints prepared by diffusion bonding on DD6 nickel-based single crystal superalloy

Journal of Materials Research and Technology, 2020
Nickel-based single crystal superalloy DD6 was diffusion bonded in vacuum at 1170 °C under 55 MPa for 2–6 h. Two processes, direct bonding and bonding with interlayer, were designed for comparison.
Yu Peng, Jinglong Li, Xuan Peng, Shiwei Li, Jiangtao Xiong, Junmiao Shi   +5 more
doaj   +1 more source