Peak friction angle estimation from joint roughness coefficient of discontinuities of limestone in Peninsular Malaysia [PDF]
The peak friction angle (φpeak) roughness of discontinuity surfaces is a value that is fundamental to the understanding of shear strength of geological discontinuities, considering its importance in determining the mechanical properties of the ...
Abdul Ghani Rafek, +5 more
core +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Angle of Repose and Angle of Marginal Stability: Molecular Dyanmics of Granular Particles
We present an implementation of realistic static friction in molecular dynamics (MD) simulations of granular particles. In our model, to break contacts between two particles, one has to apply a finite amount of force, determined by the Coulomb criterion.
Campbell C S +20 more
core +2 more sources
Reply to the discussion by Ganesh on “Analysis of passive earth pressure modification due to seepage flow effects" [PDF]
Using an assumed vertical retaining wall with a drainage system along the soil–structure interface, this paper analyses the effect of anisotropic seepage flow on the development of passive earth pressure.
Hu, Z, Wilkinson, Stephen, Yang, Z.X.
core +1 more source
SmallTalk: a novel small‐sized fusion tag for peptide expression and purification
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq +3 more
wiley +1 more source
The study of strength behavior of sandy soil mixed with plastic waste and cement slurry [PDF]
Nowadays, development of the industrial societies and urbanization caused the daily rising accumulation of plastic waste and their dispersion in the nature. To decline the environmental issues of this phenomenon, different approaches are possible.
Mehdi Khodaparast +2 more
doaj +1 more source
Theoretical and experimental study of the transport of granular materials by inclined vibratory conveyors [PDF]
A theoretical and experimental study was made of the conveying speed with which granular materials are transported by vibratory conveyors. The basic assumption made is that the layer of granular material can be considered as a point mass.
Kruyt, Nicolaas P. +2 more
core +2 more sources
The Case of a 28‐Year‐Old Woman With Medically Refractory Focal Epilepsy
ABSTRACT We present the case of a 28‐year‐old right‐handed woman with medically refractory focal epilepsy. Her seizure semiology and electroencephalography (EEG) indicated a seizure onset zone in the right central‐parietal area. However, both MRI and PET scans were unremarkable, showing no focal lesions or areas of altered metabolism.
Rishi Sharma +5 more
wiley +1 more source
Tailoring the frictional properties of granular media
A method of modifying the roughness of soda-lime glass spheres is presented, with the purpose of tuning inter-particle friction. The effect of chemical etching on the surface topography and the bulk frictional properties of grains is systematically ...
C. A. Coulomb +8 more
core +1 more source

