Results 51 to 60 of about 14,096,944 (291)
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Markov state modeling of sliding friction [PDF]
Physical Review E, 2016 9 pages, 11 ...
Pellegrini, Franco +4 more
openaire +4 more sources
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
A thermal elasto-plastic friction model for bowed-string simulation
Acta AcusticaOver the past five decades, the understanding of the stick-slip behaviour of bowed-string instruments has advanced through a combination of experimental work and physical modelling.
van Walstijn Maarten +3 more
doaj +1 more source
Modeling Friction in Modelica with the Lund-Grenoble Friction Model [PDF]
, 2002 The properties of the Lund-Grenoble friction model are summarized and different types of friction elements - bearing friction, clutch, one-way clutch, are implemented in Modelica using this friction formulation. The dynamic properties of these components are determined in simulations and compared with the friction models available in the Modelica ...
Aberger, Martin, Otter, Martin
openaire +1 more source
FEBS Open Bio, EarlyView.The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source
A review of numerical analysis of friction stir welding [PDF]
, 2014 Friction stir welding is a relatively new solid-state joining technique which is widely adopted in different industry fields to join different metallic alloys that are hard to weld by conventional fusion welding. Friction stir welding is a highly complex
He, Xiaocong, Gu, Fengshou, Ball, Andrew
core +1 more source
The Joint Vibration Analysis of a Multi-Link Surgical Manipulator
Archives of Acoustics, 2013 This paper presents a vibration analysis of a multi-link surgical micromanipulator joint, based on its detailed mathematical model. The manipulator’s prototype contains 6 links with the diameter of 8–10 [mm] and with the length of the modules of about ...
Lucyna LENIOWSKA, Ryszard LENIOWSKI
doaj
Vehicles, 2023 Inspired by the difference in the friction radii of the pads from the high-speed train brake system, stick–slip experiments for a disc–block friction system with different friction radii were carried out via a test device.
Changlin Lu +5 more
doaj +1 more source