Results 31 to 40 of about 658,266 (310)
Frontiers in Psychology, 2022 Background and AimsEnd-of-life (EoL) discussions can be difficult for seriously ill adolescents and young adults (AYAs). Researchers aimed to determine whether completing Voicing My CHOiCES (VMC)—a research-informed advance care planning (ACP) guide ...
Sima Z. Bedoya +11 more
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Deconstructing neoliberal hegemony
Cadernos do GPOSSHE On-line, 2019 Neoliberal hegemony or power is seen as the contemporary form of capitalism, a social-historical formation with three dialectically-related aspects: the state, the economic system and ideological systems.
Corinna Lotz, Penny Cole
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Dimensiuni ale spațiului în Hobbitul de J.R.R. Tolkien/ Space dimensions in J.R.R. Tolkien’s Hobbit [PDF]
Incursiuni în imaginar, 2020 In the first half of the 20th century, J.R.R. Tolkien addresses through his novel The Hobbit to people of all ages willing to imagine a different world. The mythological universe skillfully and patiently created becomes a quest into a world called Middle
Maria Holhoș, Andra Gabriela Holhoș
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Political Self-Identification of Russian Military Personnel in Finland in Spring 1917
Научный диалог, 2021 The socio-psychological characteristics of the behavior of the Russian military in Finland in the initial period of the 1917 revolution were revealed, including the formation of behavioral stereotypes, new “images of the enemy”, a change in their ideas ...
E. Yu. Dubrovskaya
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Angelaki, 2014 AbstractRelations between humans and animals occur under myriad forms and with profound richness. However, taking account of these relations often poses a considerable difficulty. That humans have a strong interest in many other animals, and that humans give rise to a reciprocal interest among many animals, is an important cultural and evolutionary ...
openaire +3 more sources
Examining the Fan Labor of Episodic TV Podcast Hosts
Transformative Works and Cultures, 2020 In podcasting—an understudied site of fan engagement—hosts of episodic TV podcasts, who are self-professed fans of a particular television series, engage in their fandom through a particular form of fan labor: producing and hosting a weekly podcast ...
Lauren Savit
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source