Frog Virus 3 DNA Replication Occurs in Two Stages [PDF]
Journal of Virology, 1982 Viral DNA synthesis in frog virus 3 (FV3)-infected cells occurs both in the nucleus and in the cytoplasm (Goorha et al., Virology 84 :32-51, 1978). Relationships between viral DNA molecules synthesized in these two compartments and their role in the virus replication were examined.
openaire +2 more sources
Adaptive immunity and histopathology in frog virus 3-infected Xenopus
Virology, 2005 Xenopus has been used as an experimental model to evaluate the contribution of adaptive cellular immunity in amphibian host susceptibility to the emerging ranavirus FV3. Conventional histology and immunohistochemistry reveal that FV3 has a strong tropism for the proximal tubular epithelium of the kidney and is rarely disseminated elsewhere in Xenopus ...
Robert, Jacques +5 more
openaire +2 more sources
Identification and characterization of the frog virus 3 DNA methyltransferase gene
Journal of General Virology, 1995 Cytosine DNA methyltransferases (MTases) first recognize specific nucleotide sequences and then transfer a methyl group from S-adenosylmethionine to cytosine. This division of function is reflected in five highly conserved motifs shared by cytosine MTases. The region containing the first four motifs is responsible for the catalytic function whereas the
K, Kaur, J, Rohozinski, R, Goorha
openaire +2 more sources
Transcriptional response of Mexican axolotls to
BMC Genomics, 2008 Background Very little is known about the immunological responses of amphibians to pathogens that are causing global population declines. We used a custom microarray gene chip to characterize gene expression responses of axolotls (Ambystoma mexicanum) to
Beachy Christopher K +4 more
doaj +1 more source
Susceptibility of Xenopus laevis tadpoles to infection by the ranavirus Frog-Virus 3 correlates with a reduced and delayed innate immune response in comparison with adult frogs [PDF]
, 2012 Xenopus laevis adults mount effective immune responses to ranavirus Frog Virus 3 (FV3) infections and clear the pathogen within 2–3 weeks. In contrast, most tadpoles cannot clear FV3 and succumb to infections within a month.
De Jesús Andino, Francisco +9 more
core +1 more source
Detection of Frog Virus 3 by Integrating RPA-CRISPR/Cas12a-SPM with Deep Learning [PDF]
A fast, easy-to-implement, highly sensitive, and point-of-care (POC) detection system for frog virus 3 (FV3) is proposed. Combining recombinase polymerase amplification (RPA) and CRISPR/Cas12a, a limit of detection (LoD) of 100 aM (60.2 copies/μL) is ...
Changyue Liu (14016369) +19 more
core +1 more source
Entry of Tiger Frog Virus (an Iridovirus) into HepG2 Cells via a pH-Dependent, Atypical, Caveola-Mediated Endocytosis Pathway [PDF]
, 2011 Tiger frog virus (TFV), in the genus Ranavirus of the family Iridoviridae , causes high mortality of cultured tiger frog tadpoles in China.
Zhao-Yu Liu +13 more
core +1 more source
Frog virus 3 replication: Analysis of structural and nonstructural polypeptides in infected BHK cells by acidic and basic two-dimensional gel electrophoresis [PDF]
, 1980 Analysis of frog virus 3-infected BHK cells by two-dimensional, acidic and basic gel electrophoresis showed that at least 90 infected cell-specific polypeptides could be detected.
Bravo, R., Kelly, D.C., Elliott, R.M.
core +2 more sources
Pathogenesis of frog virus 3 (Ranavirus sp, Iridoviridae) in the wood frog, Rana sylvatica (Lithobates sylvaticus) [PDF]
, 2015 Amphibian populations suffer massive mortalities from infection with Frog Virus 3 (FV3, Ranavirus, Iridoviridae), a pathogen also responsible for mortalities of fish and reptiles.
core
Cloning, Sequence Analysis, and Expression of the Major Capsid Protein of the Iridovirus Frog Virus 3 [PDF]
, 1996 The nucleotide sequence of the gene encoding the major capsid protein (MCP) of frog virus 3 (FV3) has been determined and compared to other iridovirus capsid genes.
GENTRY, G.A. +4 more
core +1 more source