Results 71 to 80 of about 9,722 (181)

Sequence‐encoded determinants drive distinct early aggregation pathways and different structural outcomes in PNT1 fibrils across Henipavirus members

Protein Science, Volume 35, Issue 9, September 2026.
Abstract Protein aggregation is increasingly recognized as a biologically relevant process in viral proteins, yet the molecular determinants governing such phenomena remain poorly understood. Intrinsically disordered proteins (IDPs) are ubiquitous in viral proteomes, where conformational plasticity not only enables functional diversity but also permits
Harshita Sawdekar, Julien Mignon, Frank Gondelaud, Anuja Walimbe, Samrat Mukhopadhyay, Joseph Chamieh, Sonia Longhi   +6 more
wiley   +1 more source

Survival of frog virus 3 in freshwater and sediment from an English lake [PDF]

, 2016
Ranaviruses can be transmitted by contaminated water and sediment but must retain infectivity for a sufficient period to reach and infect a susceptible host. To determine the risk a virus represents once it enters the environment, its persistence in that
McPherson, N., Bayley, A., Feist, S., Munro, J.   +3 more
core   +1 more source

Malectin Alleviates Endoplasmic Reticulum Stress in Gestational Diabetes Mellitus via Glycoprotein Quality Control Mechanisms

Advanced Science, Volume 13, Issue 46, 17 August 2026.
Malectin alleviates high glucose‐induced ER stress and damage in placental trophoblasts, a function dependent on its six critical carbohydrate‐binding residues. In a GDM mouse model, administration of TAT‐Malectin ameliorated hyperglycemia and placental ER stress and prevented fetal macrosomia.
Jiahui Zhu, Yumeng Zhang, Ye Wang, Xiaoyu Zhu, Ailin Yuan, Weijing Yin, Huangmin Yu, Xuemin Pang, Yufeng He, Yuchen Wang, Tong Wang, Yong Li, Yunlong Si   +12 more
wiley   +1 more source

Frog virus 3 prevalence in tadpole populations inhabiting cattle-access and non-access wetlands in Tennessee. [PDF]

, 2007
Ranaviruses have been associated with most of the reported larval anuran die-offs in the United States. It is hypothesized that anthropogenically induced stress may increase pathogen prevalence in amphibian populations by compromising immunity.
Baldwin, Charles A., Gray, Matthew J., Miller, Debra L., Schmutzer, Anne C.   +3 more
core  

A broadly applicable method to characterize large DNA viruses and adenoviruses based on the DNA polymerase gene

Virology Journal, 2006
Background Many viral pathogens are poorly characterized, are difficult to culture or reagents are lacking for confirmatory diagnoses. We have developed and tested a robust assay for detecting and characterizing large DNA viruses and adenoviruses.
Montgomery Roy D, Vasquez-Lee Marcia, Rudis Mary R, Hanson Larry A   +3 more
doaj   +1 more source

FROG VIRUS 3-LIKE INFECTIONS IN AQUATIC AMPHIBIAN COMMUNITIES [PDF]

Journal of Wildlife Diseases, 2008
Frog virus 3 (FV3) and FV3-like viruses, are members of the genus Ranavirus (family Iridoviridae), and they have been associated with infectious diseases that may be contributing to amphibian population declines. We examined the mode of transmission of an FV3-like virus, and potential hosts and reservoirs of the virus in a local amphibian community ...
A L J, Duffus, B D, Pauli, K, Wozney, C R, Brunetti, M, Berrill   +4 more
openaire   +2 more sources

The ageing holobiont: crosstalk between telomere dynamics, oxidative stress and the gut microbiome

Biological Reviews, Volume 101, Issue 4, Page 1877-1903, August 2026.
ABSTRACT The gut tissue is at the frontline of early onset of ageing. It exhibits high cell turnover rates and rapid telomere shortening, which can have systemic effects on the developing or senescing organism. We conducted a literature review of studies on the crosstalk between telomere length dynamics, telomerase activity, oxidative stress, and gut ...
Michael L. Pepke, Søren B. Hansen, Morten T. Limborg   +2 more
wiley   +1 more source

Nucleotide sequence of an immediate-early frog virus 3 gene [PDF]

Journal of Virology, 1984
We have used "gene walking" with synthetic oligonucleotides and M13 dideoxynucleotide sequencing techniques to obtain the complete coding and flanking sequences of the gene encoding a major immediate-early RNA (molecular weight, 169,000) of frog virus 3.
D, Willis, D, Foglesong, A, Granoff
openaire   +2 more sources

Alternative Developmental Toxicity Screening Methods Using Chick Embryo‐Based Models

Journal of Applied Toxicology, Volume 46, Issue 8, Page 2640-2649, August 2026.
ABSTRACT Nonclinical developmental toxicity studies are used to investigate the potential toxicities of drugs and chemical candidates on normal embryonic and fetal development during pregnancy, generally using mammalian laboratory animals such as rats and rabbits.
Jeong Hwan Kim, Cheoljin Park, Donghee Kim, Wonjun Jeong, Jinsoo Lee   +4 more
wiley   +1 more source

A Novel Adenovirus in Chinstrap Penguins (Pygoscelis antarctica) in Antarctica

Viruses, 2014
Adenoviruses (family Adenoviridae) infect various organ systems and cause diseases in a wide range of host species. In this study, we examined multiple tissues from Chinstrap penguins (Pygoscelis antarctica), collected in Antarctica during 2009 and 2010,
Sook-Young Lee, Jeong-Hoon Kim, Yon Mi Park, Ok Sarah Shin, Hankyeom Kim, Han-Gu Choi, Jin-Won Song   +6 more
doaj   +1 more source