Results 21 to 30 of about 254,615 (296)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
The Religious Factor in the North Caucasian Frontier Zone
Журнал Фронтирных ИсследованийWhile religious factor played a significant role in the history of the North Caucasian frontier, it was not a primary institution. Despite increased scholarly attention to the frontier dynamics of this region over the past two decades, the influence of ...
Sharafutdin A. Magaramov
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Mobility and tourist locations. The case of Martinique Island, a French territory in the Caribbean
Belgeo, 2005 This paper contributes to the analysis of the mobility system through strategic sites represented by tourist locations, mirrors of globalisation. Tourist locations exist merely through human flows: varied and complex flows between migrations and tourism.
Olivier Dehoorne, Huhua Cao
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The Virtualization of the Sociocultural Frontier “Tertius Romae.” Translation from Russian
Журнал Фронтирных ИсследованийThe article addresses the need to clarify the semantic core of the sociocultural frontier Tertius Romae. The theoretical construct of Tertius Romae, originating in the writings of Marcus Tullius Cicero, has undergone significant semantic transformations ...
Gennady V. Bakumenko, Anna G. Luginina
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Caravelle, 2019 Spanish Louisiana (1763-1803), including both eastern and western Floridas after 1783, is an exemplary cultural mosaic at the crossroads of empires.
Soizic Croguennec
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Rechtsgeschichte - Legal History, 2023 This article reviews ecclesiastical opinions on Indigenous slavery in early modern Chile, the southernmost frontier of the Spanish Empire. Generally, historiography has only analyzed missionary relations with the Mapuche people on the Mapuche-Hispanic ...
Constanza López Lamerain
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Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications
FEBS Open Bio, EarlyView.This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley +1 more source
The Problem of Ethnic Identification of the Yurt Tatars. Translation from Russian
Журнал Фронтирных ИсследованийIn contemporary historiography, the question of the ethnogenesis of the Yurt Tatars on the Astrakhan frontier remains particularly relevant. Various scholars and local historians, drawing on extensive archival sources and accounts by travellers and ...
Rastyam T. Aliev
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