Results 21 to 30 of about 246,042 (296)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

The Religious Factor in the North Caucasian Frontier Zone

open access: yesЖурнал Фронтирных Исследований
While religious factor played a significant role in the history of the North Caucasian frontier, it was not a primary institution. Despite increased scholarly attention to the frontier dynamics of this region over the past two decades, the influence of ...
Sharafutdin A. Magaramov
doaj   +1 more source

Mapping Medievalism: An Indigenous Political Perspective [PDF]

open access: yesJournal of Art Historiography, 2011
Review of Kathryn Brush (ed.), Mapping Medievalism at the Canadian Frontier, London Ontario Canada: Museum London and the McIntosh Gallery, 2010. Mapping Medievalism, a collection of essays written by a professor and nine graduate students, is an ...
Vanessa Dion Fletcher, Warren Bernauer
doaj  

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Mobility and tourist locations. The case of Martinique Island, a French territory in the Caribbean

open access: yesBelgeo, 2005
This paper contributes to the analysis of the mobility system through strategic sites represented by tourist locations, mirrors of globalisation. Tourist locations exist merely through human flows: varied and complex flows between migrations and tourism.
Olivier Dehoorne, Huhua Cao
doaj   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

The Virtualization of the Sociocultural Frontier “Tertius Romae.” Translation from Russian

open access: yesЖурнал Фронтирных Исследований
The article addresses the need to clarify the semantic core of the sociocultural frontier Tertius Romae. The theoretical construct of Tertius Romae, originating in the writings of Marcus Tullius Cicero, has undergone significant semantic transformations ...
Gennady V. Bakumenko, Anna G. Luginina
doaj   +1 more source

Rendre la justice en Louisiane espagnole (1763-1803) : aménagements, improvisations et instrumentalisations

open access: yesCaravelle, 2019
Spanish Louisiana (1763-1803), including both eastern and western Floridas after 1783, is an exemplary cultural mosaic at the crossroads of empires.
Soizic Croguennec
doaj   +1 more source

Ecclesiastics and Indigenous Slavery on the Frontier: The Case of Chile in the 16th and 17th Centuries

open access: yesRechtsgeschichte - Legal History, 2023
This article reviews ecclesiastical opinions on Indigenous slavery in early modern Chile, the southernmost frontier of the Spanish Empire. Generally, historiography has only analyzed missionary relations with the Mapuche people on the Mapuche-Hispanic ...
Constanza López Lamerain
doaj   +1 more source

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