Results 31 to 40 of about 163,275 (268)

The Virtualization of the Sociocultural Frontier “Tertius Romae.” Translation from Russian

open access: yesЖурнал Фронтирных Исследований
The article addresses the need to clarify the semantic core of the sociocultural frontier Tertius Romae. The theoretical construct of Tertius Romae, originating in the writings of Marcus Tullius Cicero, has undergone significant semantic transformations ...
Gennady V. Bakumenko, Anna G. Luginina
doaj   +1 more source

Rendre la justice en Louisiane espagnole (1763-1803) : aménagements, improvisations et instrumentalisations

open access: yesCaravelle, 2019
Spanish Louisiana (1763-1803), including both eastern and western Floridas after 1783, is an exemplary cultural mosaic at the crossroads of empires.
Soizic Croguennec
doaj   +1 more source

Ecclesiastics and Indigenous Slavery on the Frontier: The Case of Chile in the 16th and 17th Centuries

open access: yesRechtsgeschichte - Legal History, 2023
This article reviews ecclesiastical opinions on Indigenous slavery in early modern Chile, the southernmost frontier of the Spanish Empire. Generally, historiography has only analyzed missionary relations with the Mapuche people on the Mapuche-Hispanic ...
Constanza López Lamerain
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

The Problem of Ethnic Identification of the Yurt Tatars. Translation from Russian

open access: yesЖурнал Фронтирных Исследований
In contemporary historiography, the question of the ethnogenesis of the Yurt Tatars on the Astrakhan frontier remains particularly relevant. Various scholars and local historians, drawing on extensive archival sources and accounts by travellers and ...
Rastyam T. Aliev
doaj   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

open access: yesMolecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant   +7 more
wiley   +1 more source

“Urban by nature”: The Sokoto jihadist approach to urban planning

open access: yesAfriques, 2020
Like other Islamic reform and state-building movements across the pre-colonial Sahel, the Sokoto Jihad of 1804 had started genuine urbanization processes with architectural references to Islamic ideals of inhabited space.
Stephanie Zehnle
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

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