Results 41 to 50 of about 177,354 (268)

The Virtualization of the Sociocultural Frontier “Tertius Romae.” Translation from Russian

open access: yesЖурнал Фронтирных Исследований
The article addresses the need to clarify the semantic core of the sociocultural frontier Tertius Romae. The theoretical construct of Tertius Romae, originating in the writings of Marcus Tullius Cicero, has undergone significant semantic transformations ...
Gennady V. Bakumenko, Anna G. Luginina
doaj   +1 more source

Rendre la justice en Louisiane espagnole (1763-1803) : aménagements, improvisations et instrumentalisations

open access: yesCaravelle, 2019
Spanish Louisiana (1763-1803), including both eastern and western Floridas after 1783, is an exemplary cultural mosaic at the crossroads of empires.
Soizic Croguennec
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

The Problem of Ethnic Identification of the Yurt Tatars. Translation from Russian

open access: yesЖурнал Фронтирных Исследований
In contemporary historiography, the question of the ethnogenesis of the Yurt Tatars on the Astrakhan frontier remains particularly relevant. Various scholars and local historians, drawing on extensive archival sources and accounts by travellers and ...
Rastyam T. Aliev
doaj   +1 more source

“Urban by nature”: The Sokoto jihadist approach to urban planning

open access: yesAfriques, 2020
Like other Islamic reform and state-building movements across the pre-colonial Sahel, the Sokoto Jihad of 1804 had started genuine urbanization processes with architectural references to Islamic ideals of inhabited space.
Stephanie Zehnle
doaj   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

open access: yesMolecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi   +2 more
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

open access: yesFEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata   +3 more
wiley   +1 more source

The Limes of Civilization in the Novel Cold Skin by Albert Sánchez Piñol

open access: yesCastilla: Estudios de Literatura, 2014
The novel Cold Skin by Albert Sánchez Piñol is configured as a novel space around the border between civilization and barbarism, the boundary between Numano and otherness.
Rodrigo Pardo Fernández
doaj   +2 more sources

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