Results 21 to 30 of about 364,393 (335)

Progression of Behavioral Disturbances and Neuropsychiatric Symptoms in Patients With Genetic Frontotemporal Dementia

JAMA Network Open, 2021
Key Points Question Do behavioral and neuropsychiatric symptoms evolve differently in patients with distinct genetic variations for frontotemporal dementia? Findings In this cohort study of 232 patients with genetic frontotemporal dementia, patients with
A. Benussi, E. Premi, S. Gazzina, C. Brattini, E. Bonomi, A. Alberici, L. Jiskoot, J. V. van Swieten, Raquel Sánchez-Valle, F. Moreno, R. Laforce, C. Graff, M. Synofzik, D. Galimberti, M. Masellis, Carmela Tartaglia, J. Rowe, E. Finger, R. Vandenberghe, A. de Mendonça, F. Tagliavini, I. Santana, S. Ducharme, C. Butler, A. Gerhard, J. Levin, A. Danek, M. Otto, G. Frisoni, R. Ghidoni, S. Sorbi, I. Le Ber, F. Pasquier, Georgia Peakman, E. Todd, M. Bocchetta, J. Rohrer, B. Borroni   +37 more
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The Overlapping Genetics of Amyotrophic Lateral Sclerosis and Frontotemporal Dementia

Frontiers in Neuroscience, 2020
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are two diseases that form a broad neurodegenerative continuum. Considerable effort has been made to unravel the genetics of these disorders, and, based on this work, it is now clear ...
Yevgeniya A. Abramzon, P. Fratta, B. Traynor, Ruth Chia   +3 more
semanticscholar   +1 more source

Conceptual framework for the definition of preclinical and prodromal frontotemporal dementia

Alzheimer's & Dementia, 2021
The presymptomatic stages of frontotemporal dementia (FTD) are still poorly defined and encompass a long accrual of progressive biological (preclinical) and then clinical (prodromal) changes, antedating the onset of dementia.
A. Benussi, A. Alberici, K. Samra, L. Russell, C. Greaves, M. Bocchetta, S. Ducharme, E. Finger, G. Fumagalli, D. Galimberti, L. Jiskoot, I. Le Ber, M. Masellis, B. Nacmias, J. Rowe, Raquel Sánchez-Valle, H. Seelaar, M. Synofzik, J. Rohrer, B. Borroni   +19 more
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Mitochondrial ROS control neuronal excitability and cell fate in frontotemporal dementia

Alzheimer's & Dementia, 2021
The second most common form of early‐onset dementia—frontotemporal dementia (FTD)—is often characterized by the aggregation of the microtubule‐associated protein tau.
Noemí Esteras, O. Kopach, Marta Maiolino, V. Lariccia, S. Amoroso, S. Qamar, S. Wray, D. Rusakov, Morana Jaganjac, A. Abramov   +9 more
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Sex differences in the behavioral variant of frontotemporal dementia: A new window to executive and behavioral reserve

Alzheimer's & Dementia, 2021
Biological sex is an increasingly recognized factor driving clinical and structural heterogeneity in Alzheimer's disease, but its role in the behavioral variant of frontotemporal dementia (bvFTD) is unknown.
I. Illán-Gala, K. Casaletto, S. Borrego-Écija, E. Arenaza‐Urquijo, Amy Wolf, Y. Cobigo, Sheng‐Yang M. Goh, A. Staffaroni, D. Alcolea, J. Fortea, R. Blesa, J. Clarimón, M. F. Iulita, A. Brugulat-Serrat, A. Lladó, L. Grinberg, K. Possin, K. Rankin, J. Kramer, G. Rabinovici, A. Boxer, W. Seeley, V. Sturm, M. Gorno-Tempini, B. Miller, Raquel Sánchez-Valle, D. Perry, A. Lleó, H. Rosen   +28 more
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Recommendations to distinguish behavioural variant frontotemporal dementia from psychiatric disorders.

Brain : a journal of neurology, 2020
The behavioural variant of frontotemporal dementia (bvFTD) is a frequent cause of early-onset dementia. The diagnosis of bvFTD remains challenging because of the limited accuracy of neuroimaging in the early disease stages and the absence of molecular ...
S. Ducharme, A. Dols, R. Laforce, E. Devenney, F. Kumfor, J. van den Stock, Caroline Dallaire-Théroux, H. Seelaar, F. Gossink, E. Vijverberg, E. Huey, M. Vandenbulcke, M. Masellis, Calvin Trieu, C. Onyike, P. Caramelli, L. D. de Souza, A. Santillo, M. L. Waldö, R. Landin-Romero, O. Piguet, W. Kelso, D. Eratne, D. Velakoulis, M. Ikeda, D. Perry, P. Pressman, B. Boeve, R. Vandenberghe, M. Mendez, C. Azuar, R. Levy, I. Le Ber, S. Baez, A. Lerner, R. Ellajosyula, F. Pasquier, D. Galimberti, E. Scarpini, J. V. van Swieten, M. Hornberger, H. Rosen, J. Hodges, J. Diehl-Schmid, Y. Pijnenburg   +44 more
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Neuroimaging in Frontotemporal Dementia: Heterogeneity and Relationships with Underlying Neuropathology

Neurotherapeutics, 2021
Frontotemporal dementia encompasses a group of clinical syndromes defined pathologically by degeneration of the frontal and temporal lobes. Historically, these syndromes have been challenging to diagnose, with an average of about three years between the ...
Bradley T Peet, S. Spina, Nidhi Mundada, R. La Joie   +3 more
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Frontotemporal dementia with motor neuron disease

Definitions, 2020
Frontotemporal dementia with motor neuron disease (FTD-MND) is a type of frontotemporal lobar degeneration characterized by the insidious onset (between the ages of 38-78 years) of dementia-associated psychiatric symptoms (e.g.

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Neuropathologic basis of frontotemporal dementia in progressive supranuclear palsy. [PDF]

, 2019
BackgroundProgressive supranuclear palsy (PSP) is a neurodegenerative disorder characterized by neuronal loss in the extrapyramidal system with pathologic accumulation of tau in neurons and glia.
Dickson, Dennis W, Duara, Ranjan, Graff-Radford, Neil R, Josephs, Keith A, Litvan, Irene, Murray, Melissa E, Sakae, Nobutaka, Uitti, Ryan J, Wszolek, Zbigniew K   +8 more
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Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia.

Brain : a journal of neurology, 2011
Based on the recent literature and collective experience, an international consortium developed revised guidelines for the diagnosis of behavioural variant frontotemporal dementia.
K. Rascovsky, J. Hodges, D. Knopman, M. Mendez, J. Kramer, J. Neuhaus, J. V. van Swieten, H. Seelaar, E. Dopper, C. Onyike, A. Hillis, K. Josephs, B. Boeve, A. Kertesz, W. Seeley, K. Rankin, Julene K. Johnson, M. Gorno-Tempini, H. Rosen, Caroline E Prioleau-Latham, Albert S. Lee, C. Kipps, P. Lillo, O. Piguet, J. Rohrer, M. Rossor, J. Warren, Nick C Fox, D. Galasko, D. Salmon, S. Black, M. Mesulam, S. Weintraub, B. Dickerson, J. Diehl-Schmid, F. Pasquier, V. Deramecourt, F. Lebert, Y. Pijnenburg, T. Chow, F. Manes, J. Grafman, S. Cappa, M. Freedman, M. Grossman, B. Miller   +45 more
semanticscholar   +1 more source