Apathy and impulsivity in frontotemporal lobar degeneration syndromes [PDF]
Apathy and impulsivity are common and disabling consequences of frontotemporal lobar degeneration. They cause substantial carer distress, but their aetiology remains elusive.
Coyle-Gilchrist, ITS +8 more
core +3 more sources
Abstract INTRODUCTION Frontotemporal dementia (FTD) is the most common dementia in people under age 60. Although FTD is often characterized by behavioral symptoms, few national interventions address management of these symptoms. Here we describe our protocol for Support via Technology: Living and Learning with Advancing FTD (STELLA‐FTD), an ...
Allison Lindauer +7 more
wiley +1 more source
Is this a new type of primary prosopagnosia, both progressive and apperceptive?
Azusa Sugimoto1, Shinichi Koyama2, Akira Midorikawa3, Akinori Futamura1, Kiichi Ishiwata4, Kenji Ishii4, Michael W Miller5, Mitsuru Kawamura11Department of Neurology, Showa University School of Medicine, Tokyo, 2Design Psychology Unit, Department of ...
Sugimoto A +7 more
doaj
Neuropathology of frontotemporal lobar degeneration: A review
Frontotemporal lobar degeneration (FTLD) is the second most common cause of presenile dementia. Three main clinical variants are widely recognized within the FTLD spectrum: the behavioural variant of frontotemporal dementia (bvFTD), semantic dementia (SD)
Valéria Santoro Bahia +2 more
doaj +1 more source
Epidemiology of Frontotemporal Lobar Degeneration in Northern Finland
Background: Frontotemporal lobar degeneration (FTLD) is responsible for as many as every fifth case of early-onset dementia. Very few epidemiological studies of FTLD have been conducted; there are no published epidemiological data of FTLD from Finland or
Laura Luukkainen +3 more
doaj +1 more source
Sialylation patterns in cerebral amyloid angiopathy
This study is the first to localize and evaluate sialylation modifications in the context of Alzheimer's Disease and Cerebral Amyloid Angiopathy, revealing a unique disease‐specific increase in intravascular sialylation. Abstract Glycosylation is the most common form of post‐translational modification in the brain and becomes significantly altered in ...
Caitlyn Fastenau +8 more
wiley +1 more source
Frontotemporal lobar degeneration: current perspectives
The term frontotemporal lobar degeneration (FTLD) refers to a group of progressive brain diseases, which preferentially involve the frontal and temporal lobes. Depending on the primary site of atrophy, the clinical manifestation is dominated by behavior alterations or impairment of language.
Kurz, Alexander +4 more
openaire +4 more sources
Dissociation of structural and functional integrities of the motor system in amyotrophic lateral sclerosis and behavioral-variant frontotemporal dementia [PDF]
Background and Purpose: This study investigated the structural and functional changes in the motor system in amyotrophic lateral sclerosis (ALS; n=25) and behavioral-variant fronto-temporal dementia (bvFTD; n=17) relative to healthy controls (n=37 ...
Bae, Jong Seok +9 more
core +2 more sources
Cholinergic and inflammatory phenotypes in transgenic tau mouse models of Alzheimer’s disease and frontotemporal lobar degeneration [PDF]
Anna Cranston +9 more
openalex +1 more source
Executive Impairment in Huntington's Disease: Insights From a Systematic Review of the Literature
Executive dysfunction in Huntington's disease follows a selective, stage‐dependent pattern, with early deficits in psychomotor speed, cognitive flexibility, inhibition, and working‐memory updating. Progression is associated with broader impairments in planning and attention.
Simone Migliore +4 more
wiley +1 more source

