Results 131 to 140 of about 161,801 (298)
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
, 1990 "Lt Col A D Frost. EM NX70833 ? DADMS 7th Mil District RAAMC Darwin [last line obscured]".Lieutenant Colonel A. D. Frost. EM NX70833 ? Deputy Assistant Director of Medical Services, 7th Military District, Royal Australian Army Medical Corps Darwin [last ...
Frost, A. D.
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Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Interview with Tom Frost, 1994
, 1994 Frost Bank, San Antonio, Texas From his lifetime perspective as a San Antonio business and civic leader, Tom Frost says the city was transformed post --HemisFair ’68 by leaders like Congressman Henry B.
Frost, Tom, Holmesly, Sterlin, 1932-
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Modelagem semi-empírica de um refrigerador frost-free sujeito à abertura de portas [PDF]
, 2013 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia Mecânica, Florianópolis, 2013.O projeto de refrigeradores domésticos é focado não somente na redução do consumo de energia em ...
Borges, Bruno Nuernberg
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Delusional infestation complicated by gangrene and osteomyelitis requiring finger amputation
JAAD Case Reports, 2021 Julio A. Diaz-Perez, MD +5 more
doaj +1 more source
, 2012 Source: Clara Müller-Jahnke: Gedichte, herausgegeben und illustriert von Oskar Jahnke, Berlin: Buchhandlung Vorwärts, Hans Weber, [1910]
openaire +3 more sources
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
The David Frost Show - Senator Edmund S. Muskie Interviewed by David Frost [PDF]
, 1971 Senator Edmund S. Muskie interviewed by David Frost on The David Frost Show.
Muskie, Edmund S., Frost, David
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Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source