Results 131 to 140 of about 167,722 (304)

Land Grant Application- Frost, Mark (Belgrade) [PDF]

open access: yes, 2017
Land grant application submitted to the Maine Land Office for Mark Frost for service in the Revolutionary War.https://digitalmaine.com/revolutionary_war_me_land_office/1348/thumbnail ...
Frost, Mark
core  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

A qualitative sequential frost deicing salt damage model on experimental data

open access: yes, 2002
Frost and frost deicing salt resistance of cementitious materials has been the subject of numerous research projects during the past decades. Hence a large number of different frost and frost deicing salt damage mechanisms are proposed. Nevertheless none
Kaufmann, J.P. (author)
core  

Land Grant Application- Frost, Richard (Marblehead) [PDF]

open access: yes, 2017
Land grant application submitted to the Maine Land Office for Richard Frost for service in the Revolutionary War.https://digitalmaine.com/revolutionary_war_mass/1140/thumbnail ...
Frost, Richard
core  

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

Land Grant Application- Frost, Stephen (Berwick) [PDF]

open access: yes, 2017
Land grant application submitted to the Maine Land Office for Stephen Frost for service in the Revolutionary War.https://digitalmaine.com/revolutionary_war_me_land_office/1349/thumbnail ...
Frost, Stephen
core  

Frost

open access: yes, 2012
Source: Clara Müller-Jahnke: Gedichte, herausgegeben und illustriert von Oskar Jahnke, Berlin: Buchhandlung Vorwärts, Hans Weber, [1910]
openaire   +3 more sources

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

Land Grant Application- Frost, Samuel (Wayne) [PDF]

open access: yes, 2017
Land grant application submitted to the Maine Land Office on behalf of Samuel Frost for service in the Revolutionary War, by their widow Patience Billington.https://digitalmaine.com/revolutionary_war_me_land_office/1353/thumbnail ...
Frost, Samuel   +1 more
core  

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

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