Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson +2 more
wiley +1 more source
Merkel cell carcinoma data for patients in Miami, Florida: A retrospective analysis
Kayla D. Mashoudy +4 more
doaj +1 more source
Strength Degradation of Sandstone Under Coupled Loading and Freeze-Thaw Cycles: Experimental Study and Discrete Element Numerical Simulation. [PDF]
Sun Y +5 more
europepmc +1 more source
FROST – Frost Protection of Roads and Railways
We are facing a changing climate and an increasing pressure on traditional aggregate resources. Road fundaments are being designed and built differently, with different materials – and not least; exposed differently than before. At the same time – research on frost exposure and protection has been absent in our country for decades.
Kuznetsova, Elena +2 more
openaire +1 more source
Effect of terahertz irradiation on DNA damage repair in living cells
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno +3 more
wiley +1 more source
The role of stem respiration in cold-acclimation of winter-dormant Quercus robur trees under large air temperature fluctuations. [PDF]
Rodríguez-Calcerrada J +3 more
europepmc +1 more source
This music score was submitted for the Kaleidoscope 2020 Call for Scores, an open access collaboration with the UCLA Music Library.
openaire +1 more source
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
Corrigendum to "Drought driven shrinkage of surface water bodies in India" [iScience 29 (2026) 116737]. [PDF]
Niranjannaik M, Mishra V.
europepmc +1 more source
ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley +5 more
wiley +1 more source

