Results 121 to 130 of about 207,768 (344)
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Data-Based Statistical Analysis of Laboratory Experiments on Concrete Frost Damage and Its Implications on Service Life Prediction. [PDF]
Materials (Basel), 2022 Gong F +6 more
europepmc +1 more source
Insights into a long life without cancer: The case of the bowhead whale
Molecular Oncology, EarlyView.Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley +1 more source
Transportation EngineeringThis study presents a mechanics-based framework for evaluating the performance of asphalt pavements subjected to annual ground surface deformations induced by frost heave and thaw settlement.
Saeed Vosoughian, Romain Balieu
doaj +1 more source
Potential of frost damage of off-ground foundation stones in Norwegian Stave Churches since 1950 using land surface temperature. [PDF]
Heliyon, 2022 Bertolin C, Cavazzani S.
europepmc +1 more source
Cold hardening and dehardening in Salix [PDF]
, 2003 The variation in cold hardiness in Salix in the autumn was investigated using clones of different geographic origins. In late growing season, the variation was small and inversely related to a phenotypic variation in potential growth rate.
Lennartsson, Mattias
core
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Debris/ice/TPS assessment and integrated photographic analysis for Shuttle Mission STS-46 [PDF]
A Debris/Ice/TPS assessment and integrated photographic analysis was conducted for Shuttle Mission STS-46. Debris inspections of the flight elements and launch pad were performed before and after launch.
Davis, J. Bradley +2 more
core +1 more source
Frost Hardiness of Iraqi Wheat genotypes [PDF]
, 2015 Frost hardiness level in winter cereals is especially temperature dependent. The low temperature which kills 50% of plants (LT50) is considered to be a standard indicator of frost hardiness level of plant. Frost hardiness is considered the most important
Al-Issawi, M +3 more
core +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source