Results 41 to 50 of about 18,196 (278)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

The Age of Cluster Galaxies from Continuum Colors [PDF]

open access: yes, 2008
We determine the age of 1,104 early-type galaxies in eight rich clusters ($z = 0.0046$ to $0.175$) using a new continuum color technique. We find that galaxies in clusters divide into two populations, an old population with a mean age similar to the age ...
Andrew Odell   +13 more
core   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Simulation study on frost formation characteristics on the surface of cold storage evaporator [PDF]

open access: yesJournal of Hebei University of Science and Technology
Aiming at the frosting problem of evaporators in cold storage leading to significant decrease in heat transfer efficiency and damage to the cold storage, based on the theory of heat and mass transfer, combined with actual cold storage data, a modified ...
Fuqing ZHANG, Ye YAO, Haiyan QU, Bo CUI
doaj   +1 more source

One large blob and many streams frosting the nearby stellar halo in Gaia DR2 [PDF]

open access: yes, 2018
We explore the phase-space structure of nearby halo stars identified kinematically from Gaia DR2 data. We focus on their distribution in velocity and in "integrals of motion" space as well as on their photometric properties.
Helmi, Amina   +2 more
core   +3 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Analysis on frosting of heat exchanger and numerical simulation of heat transfer characteristics using BP neural network learning algorithm.

open access: yesPLoS ONE, 2021
The study is aimed at the frosting problem of the air source heat pump in the low temperature and high humidity environment, which reduces the service life of the system.
Bo Yu, Yuye Luo, Wenxiao Chu
doaj   +1 more source

Simplified modelling of air source heat pumps producing detailed results [PDF]

open access: yes, 2012
Created by the Building Research Establishment (BRE), the Standard Assessment Procedure (SAP) is the UK Government‟s recommended method of assessing the energy ratings of dwellings.
Allison, John   +3 more
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy