Results 161 to 170 of about 2,516,152 (276)

Association of uterine artery Doppler parameters and coagulation function indicators with endometrial morphology and frozen-thawed embryo transfer outcomes. [PDF]

Am J Transl Res
Cui H, He F, Guo X, Tian J.
europepmc   +1 more source

Methyl 4‐O‐Demethylbarbatate Destabilises HIF‐1α and Enhances Temozolomide Sensitivity in Glioma Cells

Cell Proliferation, EarlyView.
The lichen‐derived metabolite methyl 4‐O‐demethylbarbatate (Me‐4‐O‐DBA) suppresses glioma stemness, motility, and metabolic plasticity through inhibition of HIF‐1α signaling and synergistically enhances temozolomide activity, highlighting a potential strategy to target stemness‐driven therapeutic resistance in glioma.
Rui Zhou, Mücahit Varlı, Rundong Liu, Jieun Yu, Hyung‐Ho Ha, Jae‐Seoun Hur, Sang Kyum Kim, Hahyun Park, Hangun Kim   +8 more
wiley   +1 more source

High AMH levels are associated with late miscarriage in women with PCOS undergoing frozen-thawed embryo transfer. [PDF]

BMC Pregnancy Childbirth
Jiao Y, Liu S, Zhang W, Peng C, Wang F, Liang Y, Zhang Y, Guo Y.   +7 more
europepmc   +1 more source

SHIP1 regulates TREM2 signalling and macrophage functions in a hiPSC‐derived model

The FEBS Journal, EarlyView.
In this study, we characterised the role of SHIP1 in regulating TREM2 signalling and global microglial myeloid functions using human‐induced pluripotent stem cell (hiPSC)‐derived macrophages. Knockout of SHIP1 (SHIP1 KO) in macrophages decreased inflammatory activation and levels of scavenger receptors. SHIP1 KO macrophages also exhibited reduced TREM2
Kim S. Martin, Juliane Obst, Shania Ibarra, Emma J. Murphy, Katerina O. Gospodinova, Emma Mead   +5 more
wiley   +1 more source

The Effect of Intramuscular Human Chorionic Gonadotropin on Endometrial Preparation in Frozen-Thawed Embryo Transfer: A Randomized Clinical Trial. [PDF]

Int J Fertil Steril
Moridi M, Yahyaei A, Vesali S, Mashayekhi M.   +3 more
europepmc   +1 more source

Biocatalytic synthesis of S‐adenosyl‐l‐methionine analogues for allosteric activation of cystathionine‐β‐synthase

The FEBS Journal, EarlyView.
Cystathionine‐β‐synthase (CBS) helps remove harmful homocysteine and supports the production of protective sulfur‐containing molecules. Using its natural activator, S‐adenosyl‐l‐methionine, as a template, we designed and tested 15 analogues. Three activated and stabilized the enzyme, including the newly identified S‐2‐amino‐adenosyl‐l‐methionine. These
Dalibor Nakládal, Žaneta Zajacová, Rick Oerlemans, Jana Havlikova, Gabriel Zorkócy, Lukáš Kerti, Katarína Sujová, Adrian Lengyel, Zoë van der Gun, Christina Yoseif, Adrianus Cornelis van der Graaf, Guido Krenning, Ján Kyselovič, Vladimír Frecer, Matthew R. Groves, Zdenko Levarski, André Heeres, Rob H. Henning, Leo E. Deelman   +18 more
wiley   +1 more source

Effect of Low-Dose Estradiol on the Clinical Pregnancy Rate of the Hormone Replacement Frozen-Thawed Embryo Transfer Cycle. [PDF]

Int J Womens Health
Huang C, Liu J, Zhu Y, Zhang H, Jiang R, Jiang Y, Xing J.   +6 more
europepmc   +1 more source

Kinetic signatures of RAS–BRAF engagement reveal isoform selectivity, oncogenic amplification, and mutation‐dependent inhibitor resistance

The FEBS Journal, EarlyView.
The BRAF N terminus uses a cooperative BSR–CRD gate that restricts RAS binding to the RBD, which can be mitigated by oncogenic RAS mutations. KRAS engages BRAF through stability‐driven, long‐lived complexes, whereas NRAS binds transiently in a frequency‐driven mode.
Sravani Malasani, Zhihong Wang
wiley   +1 more source

Progesterone Levels on the Day of Frozen-thawed Embryo Transfer in Artificial Cycles with Vaginal Progesterone Do not Predict Clinical Pregnancy: a Prospective Study. [PDF]

Reprod Sci
Furlan SMP, Dias CMF, Ferriani RA, Navarro PA.   +3 more
europepmc   +1 more source

Giants in the cold: Morphological evidence for vascular heat retention in the viscera but not the skeletal muscle of the basking shark (Cetorhinus maximus)

Journal of Fish Biology, EarlyView.
Abstract Fewer than 50 of the over 30,000 extant species of fishes have developed anatomical specializations facilitating endothermy in specific body regions. The plankton‐feeding basking shark (Cetorhinus maximus), traditionally classified as an ectotherm, was recently shown to have regionally endothermic traits such as centralized red muscle (RM ...
C. Antonia Klöcker, Axel Schlindwein, Martin C. Arostegui, Ingrid M. Bruvold, Joel V. Wernström, Montserrat Martin‐Armas, David W. Sims, Nicolas Straube, Andreas Altenburger, Claudia Junge   +9 more
wiley   +1 more source