Results 181 to 190 of about 2,516,152 (276)

A review of xenobiotic membrane transporter expression within the human placenta: Lessons gained from primary tissue and in vitro methodologies

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend A summary of the current knowledge around membrane transporter expression in the most widely used in vitro models of human trophoblasts, including primary placental tissue, cancer cell lines and trophoblast stem cells, as well as the techniques to attempt to mimic the human placenta in vivo.
Rhiannon Pass   +2 more
wiley   +1 more source

Comparison of Wildtype and Recombinant Adeno‐Associated Virus (AAV) Production Reveals Distinct Productivity and Content Ratio Profiles

open access: yesBiotechnology Journal, Volume 21, Issue 11, November 2026.
Graphical Abstract and Lay Summary Wildtype and recombinant adeno‐associated virus production are compared across infection, transfection, and hybrid systems in suspension HEK293 cells. Wildtype infection achieves markedly higher vector genome titers and content ratios than triple transfection, and adenoviral helper input governs both packaging ...
Sofia Alfieri, Kelvin H. Lee
wiley   +1 more source

The effect of laser-assisted hatching on clinical outcomes of frozen-thawed embryo transfer at different embryo ages. [PDF]

open access: yesEur J Obstet Gynecol Reprod Biol X
Ou MM   +7 more
europepmc   +1 more source

Half a Century of Per‐ and Polyfluoroalkyl Substances in Northern Gannet Eggs: Impact of Regulations

open access: yesJournal of Applied Toxicology, Volume 46, Issue 11, Page 4085-4098, November 2026.
ABSTRACT Per‐ and polyfluoroalkyl substances (PFAS), known as “forever chemicals”, are persistent organic pollutants that have been widely used in the industry across the globe for many decades. Their chemical stability, bioaccumulation, and toxicity pose major environmental and health risks. This study examines temporal trends in the concentrations of
Anaïs Fournier   +2 more
wiley   +1 more source

Integrated Reproductive and Cytogenetic Assessment of Infertility in a Captive Jaguar (Panthera onca)

open access: yesVeterinary Medicine and Science, Volume 12, Issue 6, November 2026.
Integrated reproductive and cytogenetic assessment of infertility in a captive jaguar pair identified normal chromosomal status in both individuals, whereas impaired semen quality in the male likely represents a major limiting factor for reproductive success under the observed conditions.
Marie Altmanová   +3 more
wiley   +1 more source

Biallelic Truncating Variant in LRGUK Is Associated With Severe Multiple Morphological Abnormalities of the Sperm Flagella and Sperm Nuclear Defects in Humans

open access: yesClinical Genetics, Volume 110, Issue 5, Page 538-548, November 2026.
A homozygous truncating variant in LRGUK results in loss of the LRGUK protein and causes multiple morphological abnormalities of the flagella (MMAF), disrupted axonemal architecture, central pair defects, abnormal chromatin organization, and severe male infertility, establishing LRGUK as a novel human infertility gene.
Wiâme Mokkedem   +14 more
wiley   +1 more source

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