Results 201 to 210 of about 2,389,697 (294)

Mitochondrial DNA in Tumor Evolution and Heterogeneity: Characteristics, Technological Advances, Applications and Challenges

open access: yesMedComm – Oncology, Volume 5, Issue 3, September 2026.
This review highlights mitochondrial DNA (mtDNA) somatic mutations as an emerging and potent endogenous lineage marker, offering distinct advantages over traditional nuclear genomic (nDNA) approaches. Lineage tracing based on mtDNA mutations has matured into an indispensable tool, providing unprecedented insights into tumor biology and holding ...
Zifeng Ruan   +4 more
wiley   +1 more source

Impact of Tamoxifen on Endometrial Thickness in Women With Thin Endometrium Following Estrogen Therapy During Frozen-Thawed Embryo Transfer. [PDF]

open access: yesClin Case Rep
Zaree M   +6 more
europepmc   +1 more source

Self‐Organized Vascularized Human Liver Spheroids: Serum‐Free Culture Conditions and Use as Tissue Building Blocks

open access: yesSmall, Volume 22, Issue 49, 1 September 2026.
This approach addresses a major challenge in tissue engineering: creating larger, vascularized tissues. Microvascular networks in liver spheroids are developed through self‐organization mediated by mesenchymal stem cells. These spheroids are maintained in serum‐reduced or serum‐free medium and serve as building blocks to form planar tissue layers ...
Alina Filatova   +10 more
wiley   +1 more source

Mito‐TEMPO Improves Post‐Thaw Quality and Fertilizing Capacity of Rooster Semen Cryopreserved in Beltsville Extender

open access: yesVeterinary Medicine and Science, Volume 12, Issue 5, September 2026.
This study reported the effect of Mito‐TEMPO on rooster semen quality cryopreserved in Beltsville extender. Semen diluted in extenders containing 10 or 100 µM of Mito‐TEMPO presented higher motility, average path velocity as well as membrane/acrosome integrity, mitochondrial activity, and fertility rate; and lower lipid peroxidation, apoptosis rate ...
Mahdi Mokhtari   +3 more
wiley   +1 more source

hTERT Immortalization Stabilizes Human Umbilical Cord MSCs and Maintains Their Small Extracellular Vesicles With Preserved Immunomodulatory Activity and Primordial Follicle‐Activating Capacity

open access: yesAging Cell, Volume 25, Issue 9, September 2026.
hTERT immortalization stabilizes hUCMSC‐derived sEV function by alleviating cellular senescence and preserving young‐like cargo profiles. H11‐sEVs retain immunomodulatory activity, primordial follicle‐activating capacity, and ovarian protective effects.
Yating Chen   +7 more
wiley   +1 more source

The Secretome Derived From Human Umbilical Cord Mesenchymal Stem Cells Improves Skin Photoaging by Enhancing Mitophagy to Inhibit the cGAS‐STING Pathway

open access: yesAging Cell, Volume 25, Issue 9, September 2026.
HUC‐MSC‐derived SCT alleviates UV‐induced skin photoaging. It acts by enhancing mitophagy to clear damaged mitochondria, thereby suppressing the pro‐inflammatory cGAS‐STING pathway. This work identifies SCT as a novel cell‐free therapy targeting mitochondrial quality control to counteract sterile inflammation in aging. ABSTRACT Ultraviolet (UV)‐induced
Tingting Tang   +13 more
wiley   +1 more source

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