Mitochondrial Haplotype Shapes the Trajectory of Ovarian Aging in Genetically Heterogeneous Rats
Using genetically heterogeneous rats carrying divergent mitochondrial haplotypes on a randomized nuclear background, we show that mtDNA variation modifies the rate of ovarian aging. OKC‐HETW ovaries showed bioenergetic deficits, reduced mtDNA copy number, and impaired TFAM–mtDNA binding by 4 months of age, with early fibrosis and immune infiltration ...
Subhasri Biswas +11 more
wiley +1 more source
Impact of endometrial thickness on reproductive outcome in fresh and frozen-thawed embryo transfer: systematic review and meta-analysis. [PDF]
Pérez-Milán F +10 more
europepmc +1 more source
Improvement of Mouse Spermatozoa Freezing at −80°C With Ascorbic Acid 2‐Glucoside at Thawing Phase
ABSTRACT Background Sperm cryopreservation is the most common method to maintain a great number of mutant mouse lines. However, the use of liquid nitrogen (LN2) for freezing presents considerable problems in terms of cost, safety, and accessibility. For this reason, the storage of semen samples at ‐80° in ultra‐freezers has been increasingly used in ...
Alessia Paradiso +6 more
wiley +1 more source
Repeated cryopreservation is associated with poor pregnancy outcomes after frozen-thawed embryo transfer in women aged < 35 years: a propensity-score matched cohort study. [PDF]
Huang Z +5 more
europepmc +1 more source
ABSTRACT Background Sperm acquire fertility ability during epididymal maturation mainly in the epididymal caput and corpus, and once matured, are stored in the epididymal cauda. During storage, interactions with cauda epididymosomes (epEVs) may influence sperm fertility potential; however, the role of such interactions on sperm fertility remains ...
Maíra Bianchi Rodrigues Alves +7 more
wiley +1 more source
The Association Between Pre-cycle Maternal Vitamin D Status and Reproductive Outcomes in Frozen-Thawed Embryo Transfer: A Systematic Review and Meta-Analysis. [PDF]
Abdelgader MAA +9 more
europepmc +1 more source
Summary Targeting the colony‐stimulating factor 1 receptor (CSF1R) to remove tumour‐associated macrophages is being explored as cancer therapy. This strategy may be relevant for chronic lymphocytic leukaemia (CLL), which strongly depends on support from myeloid cells.
Natascha Rosen +14 more
wiley +1 more source
First-Trimester Uterine Artery Doppler Indices and Pregnancy Outcomes in Naturally Conceived and Frozen-Thawed Embryo Transfer Cycles. [PDF]
Aygün EG, Kahraman E.
europepmc +1 more source
ABSTRACT The Antarctic copepod, Boeckella poppei, occurs in maritime freshwater lakes on sub‐Antarctic islands, Antarctic Islands and the Antarctic continent, but no previous studies assess the thermal tolerance behind this broad geographic distribution.
Katherine A. Reed +3 more
wiley +1 more source
Impact of different endometrial preparation protocols on pregnancy outcomes in frozen-thawed embryo transfer cycles among patients ≤35 years with a history of intrauterine adhesion separation surgery: a retrospective cohort study. [PDF]
Sun H +5 more
europepmc +1 more source

