Results 171 to 180 of about 86,491 (358)

Tetrastigma Hemsleyanum Polysaccharide Suppresses Triple‐Negative Breast Cancer by Disrupting the Hippo‐YAP/TEAD4‐PDIA4 Axis and Endoplasmic Reticulum Stress Adaptation

Advanced Science, EarlyView.
ABSTRACT Triple‐negative breast cancer (TNBC) exhibits addiction to chronic endoplasmic reticulum (ER) stress, which sustains an aggressive metastatic phenotype through activation of the unfolded protein response (UPR). Here, we identify a previously unrecognized “ER‐stress addiction” axis in which the Hippo pathway effector TEAD4 directly ...
Yini Shang, Wentao Si, Youxue Zhang, Jialin Liu, Huaixi Zhang, Yafei Li, Hongmeng Su, Wei Jiang, Zhishan Ding, Lihong Wang   +9 more
wiley   +1 more source

Endometrial mirnome during the implantation windows can predict early miscarriage or live birth after fresh or frozen embryo transfer [PDF]

, 2017
L. Drissennek, Frida Entezami, A. Gala, C. Vincens, D. Haouzi, S. Hamamah   +5 more
openalex   +1 more source

Immunoisolation of centrosomes from Drosophila melanogaster [PDF]

, 2005
Lange, B., Lehmann, V., Müller, H.
core   +2 more sources

Myeloid‐Derived Grancalcin Promotes Periodontal Inflammation and Pathological Bone Remodeling in Periodontitis

Advanced Science, EarlyView.
Grancalcin (GCA), a myeloid‐derived protein, is enriched in gingival tissues of periodontitis patients and mouse models. Through interactions with CD44 and activation of MYH9, GCA promotes NF‐κB signaling and exacerbates periodontal inflammation and bone loss.
Min Zhou, Yao Xiao, Ziyue Xu, Chengyu Yang, Jiang Li, Ya Liu, Ping Yin   +6 more
wiley   +1 more source

Patients Often Ask if They Should Vitrify Grade C/Fair Quality Blastocysts; Tell Them Yes, as They Can Result in Almost a 30% Frozen Embryo Transfer Pregnancy Rate [PDF]

, 2015
J. Barritt, M. Surrey, H. Danzer, S. Ghadir, Wendy Chang, David Hill   +5 more
openalex   +1 more source

Exposing dairy bulls to high temperature-humidity index during spermatogenesis compromises subsequent embryo development in vitro [PDF]

, 2020
Broekhuijse, Marleen L.W.J., de Cássia Bicudo, Luana, de Souza Ramos Angrimani, Daniel, Demeyere, Kristel, Llamas Luceno, Núria, Meyer, Evelyne, Mullaart, Erik, Peelman, Luc, Szymańska-Vandendriessche, Katarzyna, Van Poucke, Mario, Van Soom, Ann   +10 more
core   +2 more sources

SMAD4 Palmitoylation Drives a Metabolic‐Transcriptional Circuit to Promote Tumorigenesis and Confers Radiosensitivity in Pancreatic Cancer

Advanced Science, EarlyView.
This study identifies palmitoylation as a novel regulatory modification of SMAD4, mediated by ZDHHC22/APT2. It activates fatty acid synthesis, creating a self‐reinforcing SMAD4–FASN–palmitate feedback loop that drives pancreatic cancer growth and enhances radiotherapy sensitivity.
Yang Wang, Shan Zhang, Junping Bai, Xiaobing Li, Yi Han, Min Ji, Chongyi Jiang, Xiaobei Ge, Tianyu Yu, Yongying Hou, Jun Zhang, Wangting Li, Yiran Song, Jiaying Cai, Yingqun Zhou, Liwei An, Feng Wang   +16 more
wiley   +1 more source

Mitochondria and Neuromast Tagging With Fluorescent Gallium‐Triapine Analogues: In Cellulo MP FLIM and Zebrafish Live Imaging

Advanced Science, EarlyView.
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green, Michael W. Jones, Merissa Saleem, Haobo Ge, Melita Tvardauskaite, Julia Dudzic, Fernando Cortezon‐Tamarit, Rory L. Arrowsmith, Charareh Pourzand, Gabriele Kociock‐Kohn, Nicholas H. Rees, Jonathan R. Dilworth, Stephen Faulkner, Stanley W. Botchway, David Gurevich, Sofia I. Pascu   +15 more
wiley   +1 more source

Hyperbaric oxygen therapy: a possible choice for patients with resistant thin endometrium during frozen embryo transfer treatments [PDF]

, 2023
Jingjing Chen, Fangling Huang, Jing Fu, Jianjuan Zhao, Jinsheng Li, Zhengrong Peng, Jing Zhao, Bin Xu, Shuyi Li, Qiong Zhang, Shaolin Liang, Yanping Li   +11 more
openalex   +1 more source

A fresh(er) perspective on frozen embryo transfers [PDF]

Fertility and Sterility, 2016
Nigel, Pereira, Zev, Rosenwaks
openaire   +2 more sources