Results 61 to 70 of about 77,009 (255)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Survey on Frozen Fish Consumption Pattern among Selected Households in Obio/Akpor Local Government Area of Rivers State, Nigeria

open access: yesAgricultura, 2016
The study focused on frozen fish consumption pattern among selected households in Obio/Akpor Local Government Area (OBALGA). One hundred (100) households were randomly selected from ten (10) communities in the Local Government Area.
Caroline 0binedo Albert
doaj   +1 more source

On the Frozen “Otoshimi” (Crushed Fish Meat)

open access: yesNIPPON SUISAN GAKKAISHI, 1951
Fishes are frozen usually in such forms as “round” and “Otoshimi” and “fillet” We tried to freeze fishes in a new form, “Otoshimi” (crushed fish meat), whiche is suitable for the transportation and the raw material of foods. This crushed meat was prepared as follows.
Katsuzi YOSHIMURA   +3 more
openaire   +2 more sources

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Chemical changes in silver carp (Hypophthalmichthys molitrix) minced muscle during frozen storage: Effect of a previous washing process

open access: yesGrasas y Aceites, 2010
Silver carp (Hypophthalmichthys molitrix) has acquired great attention because of its increasing farming production and application in the surimi-product commercialization.
Afsaneh Asgharzadeh   +3 more
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Effect of Temperature Change in Circulation on Quality and Biogenic Amine Content of Frozen Fish Dumplings

open access: yesShipin gongye ke-ji
The aim of this study was to investigate the effect of temperature changes in circulation on the quality and biogenic amine content of frozen fish dumplings and its intrinsic mechanism. The fish dumplings were flash frozen at −25 ℃ and then stored at −7 ℃
Jiayin MA   +4 more
doaj   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

open access: yesFEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo   +7 more
wiley   +1 more source

Quick-FISH: A Rapid Fluorescence In Situ Hybridization Technique for Molecular Cytogenetic Analysis

open access: yesBioTechniques, 1998
A rapid and simplified fluorescence in situ hybridization (FISH) technique for the detection of human chromosome-specific centromeric probes is described.
Sushanta K. Banerjee   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy