Results 121 to 130 of about 10,894 (204)

An investigation into the binding of sheep heart phosphofructokinase to an intracellular component : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry at Massey University [PDF]

open access: yes, 1987
Phosphofructokinase (E.C.2.7.1.11) is an ambiquitous enzyme; ie it can be located either in a cytosolic or particulate form, depending on the metabolic status of the cell.
Neil, Teresa Kathleen
core  

Giardia unveiled: a proteome view of the parasite in search of drug, vaccine and diagnostic targets

open access: yesParasitology
Giardiasis remains a significant global health burden, constrained by limited diagnostic tools, the emergence of drug-resistant Giardia lamblia strains, and the absence of a licenced human vaccine.
Lorena González-López   +7 more
doaj   +1 more source

ALDOA‐Mediated Metabolic Reprogramming is a Targetable Vulnerability for Ferroptosis Sensitization in Cancer

open access: yesAdvanced Science
Ferroptosis presents great potential for cancer therapy, either alone or in combination with classical therapy. However, inducing ferroptosis by targeting canonical ferroptosis suppressors that directly inhibit lipid peroxidation non‐selectively induces ...
Pengqi Wang   +6 more
doaj   +1 more source

Melatonin Improves Salt Tolerance in Tomato Seedlings by Enhancing Photosystem II Functionality and Calvin Cycle Activity

open access: yesPlants
Salt stress severely impairs photosynthesis and development in tomato seedlings. This study investigated the regulatory role of exogenous melatonin (MT) on photosynthetic performance under salt stress by determining chlorophyll content, chlorophyll a ...
Xianjun Chen   +6 more
doaj   +1 more source

Knockout of the sulfide: quinone oxidoreductase SQR reduces growth of HCT116 tumor xenograft

open access: yesRedox Biology
Colorectal cancer (CRC) exhibits significant diversity and heterogeneity, posing a requirement for novel therapeutic targets. Polysulfides are associated with CRC progression and immune evasion, but the underlying mechanisms are not fully understood ...
Ting Lu   +7 more
doaj   +1 more source

Integrated metabolome, proteome, and transcriptome analysis explored the molecular mechanism of phosphoglycerate kinase 1 and pyruvate kinase M2 characterizing the postmortem meat quality

open access: yesFood Frontiers
Phosphoglycerate kinase 1 (PGK1) and pyruvate kinase M2 (PKM2) have been identified as the postmortem meat quality biomarkers. However, the precise molecular mechanism through which they affect and regulate the development of meat quality remains unclear.
Caiyan Huang   +6 more
doaj   +1 more source

Fibroblast-Like Synoviocytes Glucose Metabolism as a Therapeutic Target in Rheumatoid Arthritis. [PDF]

open access: yes, 2019
Metabolomic studies show that rheumatoid arthritis (RA) is associated with metabolic disruption that may be therapeutically targetable. Among them, glucose metabolism and glycolytic intermediaries seem to have an important role in fibroblast-like ...
de Oliveira, Patricia Gnieslaw   +4 more
core   +1 more source

Metabolism of lactose by Clostridium thermolacticum growing in continuous culture [PDF]

open access: yes, 2018
The objective of the present study was to characterize the metabolism of Clostridium thermolacticum, a thermophilic anaerobic bacterium, growing continuously on lactose (10gl−1) and to determine the enzymes involved in the pathways leading to the ...
Collet, Christophe   +4 more
core  

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