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Metformin reduces liver glucose production by inhibition of fructose-1-6-bisphosphatase

open access: yesNature Medicine, 2018
Metformin is a first-line drug for the treatment of individuals with type 2 diabetes, yet its precise mechanism of action remains unclear. Metformin exerts its antihyperglycemic action primarily through lowering hepatic glucose production (HGP).
Louise Lantier   +2 more
exaly   +2 more sources

Toward biomass-derived renewable plastics: Production of 2,5-furandicarboxylic acid from fructose

open access: yesScience Advances, 2018
A process for converting fructose to 2,5-furandicarboxylic acid, a monomer used in the production of a renewable plastics. We report a process for converting fructose, at a high concentration (15 weight %), to 2,5-furandicarboxylic acid (FDCA), a monomer
Ali Hussain Motagamwala   +2 more
exaly   +2 more sources
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Hereditary Fructose Intolerance

Baillière's Clinical Gastroenterology, 1990
Hereditary fructose intolerance (HFI) is an inborn error of carbohydrate metabolism that is inherited as an autosomal recessive condition. The disease is caused by a catalytic deficiency of aldolase B and is characterized by severe abdominal symptoms and hypoglycaemia which follow the ingestion of fructose, sucrose or sorbitol.
N C, Cross, T M, Cox
openaire   +5 more sources

Fructose absorption

The American Journal of Clinical Nutrition, 1993
Fructose found in modern diets as a constituent of the disaccharide sucrose is absorbed by a well-characterized absorptive system integrating enzymatic hydrolysis of the disaccharide and transfer of the resulting two monosaccharides through the apical membrane of the epithelial cell.
J E, Riby, T, Fujisawa, N, Kretchmer
openaire   +2 more sources

1,5-Anhydro-d-fructose from d-fructose

Carbohydrate Research, 2007
1,5-anhydro-D-fructose was efficiently prepared from D-fructose via regiospecific 1,5-anhydro ring formation of 2,3-O-isopropylidene-1-O-methyl(tolyl)sulfonyl-D-fructopyranose and subsequent deprotection.
Gyula, Dekany   +6 more
openaire   +2 more sources

Fructose for Dialysis

Annals of Internal Medicine, 1971
Excerpt To the editor: Dr. Tenckhoff drew attention in the August issue (Ann Intern Med75:313-314, 1971) to some hazards of peritoneal dialysis with hypertonic solutions, in particular, hypernatrem...
M, Robson, J B, Rosenfeld
openaire   +2 more sources

Fructose-sorbitol malabsorption

Current Gastroenterology Reports, 2009
Important dietary carbohydrates such as fructose and sorbitol are incompletely absorbed in the normal small intestine. This malabsorption is sometimes associated with abdominal complaints and diarrhea development, symptoms indistinguishable from those of functional bowel disease.
Fernando, Fernández-Bañares   +2 more
openaire   +2 more sources

Fructose and diabetes

The American Journal of Medicine, 1957
Abstract The metabolic effects of fructose have been studied in one healthy subject and in eight diabetic patients by observing their metabolic balance while feeding them continuously with a synthetic liquid diet containing fructose as the sole carbohydrate. In each case treatment with insulin was stopped.
J A, MOORHOUSE, R M, KARK
openaire   +2 more sources

FRUCTOSE-INDUCED HYPERURICÆMIA

The Lancet, 1967
Abstract The effect of intravenous or oral fructose, 0.5 g. per kg. body-weight, has been determined in children with hereditary fructose intolerance (H.F.I.), control children, and a man with essential fructosuria. Uric-acid levels in both urine and serum rose dramatically, indicating increased uric-acid production, in controls and children with H.F ...
J, Perheentupa, K, Raivio
openaire   +2 more sources

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