Results 51 to 60 of about 19,821 (199)

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Normal glucose metabolism in carnivores overlaps with diabetes pathology in non-carnivores [PDF]

, 2013
Carnivores, such as the dolphin and the domestic cat, have numerous adaptations that befit consumption of diets with high protein and fat content, with little carbohydrate content.
Schermerhorn, Thomas
core   +2 more sources

Chronic, Environmentally Relevant PM2.5 Exposure Exacerbates Metabolic Dysfunction‐Associated Steatotic Liver Disease and Early‐Stage Renal Dysfunction in a Rodent Model

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT While epidemiological studies link fine particulate matter (PM2.5) exposure to metabolic dysfunction‐associated steatotic liver disease (MASLD) and renal dysfunction, a translational gap exists, as most animal models utilize acute, high‐dose exposures that poorly reflect chronic, moderate‐level human scenarios.
Yi‐Siao Chen, Hugo You‐Hsien Lin, Chien‐Tzu Lin, Si‐Hua Huang, Ming‐Lun Yeh, Ming‐Lung Yu, Jin‐Ching Lee, Yao‐Chi Chung, Wei‐Ming Li, Ching‐Chia Li, Shiu‐Feng Huang, Chia‐Hung Yen   +11 more
wiley   +1 more source

Synergistic Effects of Salinization and Artificial Root Exudates on Soil Phosphatase Activity in Coastal Soil

Land Degradation &Development, EarlyView.
ABSTRACT Coastal soil salinization from rising seawater levels has adverse impacts on soil function, seed germination, and plant growth. Root exudates play a key role in supporting microbial activity, nutrient cycling, and plant health, yet little is known about the combined effects of salinization and the addition of artificial root exudates (AREs) on
Nicolina Lentine, Sarah E. Krisak, Dirk W. Vanderklein, Matthew S. Schuler, Nina M. Goodey   +4 more
wiley   +1 more source

Intolerância hereditária à frutose.

Acta Médica Portuguesa, 1998
Hereditary fructose intolerance (HFI) is a rare autosomal recessive, metabolic disorder, that results from a deficiency of aldolase B (fructose-biphosphate aldolase) in the liver, kidney and intestine.
A I Lopes, A G Almeida, A E Costa, A Costa, M Leite   +4 more
doaj   +1 more source

The mechanisms of action of metformin [PDF]

, 2017
Metformin is a widely-used drug that results in clear benefits in relation to glucose metabolism and diabetes-related complications. The mechanisms underlying these benefits are complex and still not fully understood.
A Martin-Montalvo, A Natali, AK Madiraju, AR Cameron, CA Bannister, CJ Bailey, CJ Bailey, CS Zhang, D Kirpichnikov, D Preiss, D. Grahame Hardie, DG Hardie, DS Wang, Ewan R. Pearson, F Cabreiro, FA Duca, FA Ross, G Schafer, G Zhou, GG Graham, Graham Rena, H Muller, HCS Howlett, HCS Howlett, HJ Pryor, HR Bridges, JA Baur, JB Buse, JJ Howell, JM Corton, K Forslund, K Patel, K Zhou, K Zhou, K Zhou, L Logie, L Wu, LC Gormsen, LJ McCreight, LX Cubeddu, M Foretz, M Johanns, M Massollo, MD Fullerton, MF Vincent, MR Owen, MY El-Mir, NR Shin, P Repiscak, PA Lochhead, RA DeFronzo, RA Miller, SA Hawley, SB Vasamsetti, SH Koo, T Dujic, T Dujic, X Quan, Y Shu   +58 more
core   +3 more sources

Review of nutrition management of pediatric intestinal pseudo‐obstruction

Nutrition in Clinical Practice, EarlyView.
Abstract Chronic intestinal pseudo‐obstruction (CIPO) is a rare, heterogeneous, and debilitating disorder characterized by profound intestinal dysmotility and severe nutrition challenges. Its presentation resembles that of mechanical bowel obstruction, but CIPO occurs in the absence of luminal obstruction.
Senthilkumar Sankararaman, Raisa Rani James, Bushra El‐Amaireh, Andrea Adler, Kadakkal Radhakrishnan, Sujithra Velayuthan   +5 more
wiley   +1 more source

Helicobacter pylori infection and lactose intolerance increase expiratory hydrogen

EXCLI Journal : Experimental and Clinical Sciences, 2022
Infection with Helicobacter pylori (H.pylori) may cause dyspepsia and/or unexplained functional nonspecific, gastrointestinal complaints of the irritable bowel syndrome (IBS) spectrum. Hitherto, in H.
Wolfgang J. Schnedl, Nathalie Meier-Allard, Michael Schenk, Sonja Lackner, Dietmar Enko, Harald Mangge, Sandra J. Holasek   +6 more
doaj   +1 more source

Cannabidiol and cannabigerol ameliorate steatotic liver disease via phosphocreatine buffering and lysosomal restoration

British Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) and cannabigerol (CBG) alleviate hepatic steatosis in obese mice by shifting energy buffering towards phosphocreatine and enhancing lysosomal lipid degradation and trafficking. These effects are associated with increased creatine kinase activity and lysobisphosphatidic acid (LBPA) levels, highlighting a previously unrecognised ...
Radka Kočvarová, Shahar Azar, Bella Agranovich, Ifat Abramovich, Saveliy Kirillov, Alina Nemirovski, Saja Baraghithy, Inbar Plaschkes, Emmanuelle Merquiol, Alexander Rouvinski, Galia Blum, Liad Hinden, Joseph Tam   +12 more
wiley   +1 more source

Analysis of DTC nutrigenetic services in Italy: state of the art, agreement to the ESHG statement and future outlooks [PDF]

, 2012
Background: In both USA and Europe operate companies selling Direct-to-consumer genetic tests (DTC). These tests are offered to healthy people aiming to identify predispositions to complex diseases and to take preventive measures.
Alessandra Cianflone, Antonella Monticelli, Fabio Acquaviva, Imma Castaldo, Michele Pinelli, Paola Vergara, Sergio Cocozza, Vincenzo Cinque   +7 more
core   +1 more source