Results 101 to 110 of about 645,788 (336)

Homoisoflavanone Delays Colorectal Cancer Progression via DNA Damage‐Induced Mitochondrial Apoptosis and Parthanatos‐Like Cell Death

open access: yesAdvanced Science, EarlyView.
Homoisoflavanone (HIF), a bioactive compound isolated from Polygonatum kingianum, selectively suppresses colorectal cancer progression by inducing DNA damage‐mediated mitochondrial apoptosis and parthanatos‐like cell death. HIF triggers mitochondrial dysfunction, including depolarized membrane potential, elevated ROS, and ATP depletion, while impairing
Hongjie Fan   +12 more
wiley   +1 more source

Pendugaan Parameter Genetik Populasi Cabai (Capsicum Annuum L.) melalui Pengujian F1 Hasil Persilangan secara Diallel [PDF]

open access: yes, 2014
The objective of this research were to estimate genetic parameters such as variability, heritability, general combining ability (GCA), and specific combining ability (SCA), of various agronomic traits in Chili population through diallel cross.
alfian, D. (Dedy)   +2 more
core  

Domestication of Tartary Buckwheat Shaped a Regulatory Module for Seedling Salt Tolerance by Targeting the Magnesium Transporter Gene FtMGT2

open access: yesAdvanced Science, EarlyView.
Domestication of Tartary buckwheat is selected for a salt tolerance mechanism involving the magnesium transporter FtMGT2. Its expression is controlled by the FtAGL16‐FtMYB15L module, which is stabilized under salt stress through a competitive interaction that blocks its degradation by the E3 ligase FtBRG1, ultimately boosting Na⁺ efflux and plant ...
Xiang Lu   +23 more
wiley   +1 more source

The Mitochondrial Guardian α‐Amyrin Mitigates Alzheimer's Disease Pathology via Modulation of the DLK‐SARM1‐ULK1 Axis

open access: yesAdvanced Science, EarlyView.
Dietary habits play a key role in chronic diseases, and higher annual consumption of fruit and vegetable may lower risk of dementia. Artificial intelligence predicts the lipid‐like compound α‐Amyrin (αA) from plants with edible peels as a drug candidate against Alzheimer's disease.
Shu‐Qin Cao   +36 more
wiley   +1 more source

Low YTHDC1 Expression Upregulates FSCN1 to Promote Nuclear F‐Actin Formation and Facilitate Double‐strand DNA Breaks Repair in TMZ‐Resistant Glioblastoma

open access: yesAdvanced Science, EarlyView.
This study revealed that low expression of YTHDC1 in TMZ‐resistant GBM cells leads to increased FSCN1 expression, which is suppressed by m6A modification. FSCN1 activates the CDC42/N‐WASP/Arp2/3 axis in the cell nucleus by recruiting the guanine nucleotide exchange factor (GEF) family member FGD1, thereby promoting F‐actin polymerization in the nucleus.
Minglong Yang   +9 more
wiley   +1 more source

Uji Beberapa Tricho-kompos Terformulasi Terhadap Pertumbuhan Dan Produksi Cabai Merah [PDF]

open access: yes, 2015
This research aims to determine the influence some of the Tricho-compost formulated and to get the best Tricho-compost formulated in improving the growth and yield of red chilli.
Adiwirman, A. (Adiwirman)   +2 more
core  

Pemacuan Pertumbuhan Melon (Cucumis Melo L.) dengan Cendawan Mikoriza Arbuskula dan Bakteri Azospirillum SP. [PDF]

open access: yes, 2016
Melon (Cucumis melo L.) is a high economic value horticultural crop that is cultivated in some regions of Indonesia under fertilization management. Application of inorganic fertilizer continuously can reduce soil microbial abundance.
Sukarno, D. N. (dan)   +2 more
core   +3 more sources

AI‐Directed 3D Printing of Hierarchical Polyurethane Foams

open access: yesAdvanced Science, EarlyView.
Digitally guided direct ink writing, combined with AI‐generated design, enables the fabrication of hierarchical polyurethane foams with tunable multiscale porosity. This approach produces architected foams featuring interconnected open‐cell networks and tailored mechanical properties, advancing the development of adaptive, high‐performance materials ...
Dhanush Patil   +15 more
wiley   +1 more source

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