Lateral geniculate nucleus histopathology in the rat experimental model of African trypanosomosis [PDF]
, 2017 Trypanosomosis is an infectious disease of humans and animals characterized by sleep/wake disturbances and disruptions in other circadian rhythm activities. The disease is caused by protozoan parasites of the genus Trypanosoma and transmitted by the bite
Maina, C.I., Ng’wena, G.M.
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Plasma ACTH concentration and pituitary gland histo-pathology in rats infected with [PDF]
, 2018 Background: Human African trypanosomiasis is one of the neglected and re-emerging infectious diseases in Africa with over 60 million people being at risk of contracting the disease.Objective: To investigate the effects of Trypanosoma brucei brucei ...
Maina, Charles Irungu
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Genotoxicity profile of fexinidazole—a drug candidate in clinical development for human African trypanomiasis (sleeping sickness) [PDF]
, 2017 The parasitic disease human African trypanomiasis (HAT), also known as sleeping sickness, is a highly neglected fatal condition endemic in sub-Saharan Africa, which is poorly treated with medicines that are toxic, no longer effective or very difficult to
Bourdin Trunz, Bernadette +2 more
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Role of Cytokines in Trypanosoma brucei-Induced Anaemia: A Review of the Literature [PDF]
, 2015 Background: Anaemia is an important complication of trypanosomiasis. The mechanisms through which trypanosomal infection leads to anaemia are poorly defined.
Chisi, J +3 more
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Sleeping Sickness in Liberia – A Historical Review [PDF]
, 2018 Sleeping sickness or Human African Trypanosomiasis (HAT) caused by Trypanosoma brucei gambiense is a vector-borne protozoan disease occurring in central and western Africa. HAT caused devastating epidemics during the last century.
Gangpala,, Lincoln, Mehlitz, Dieter
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Aryl Phosphoramidates of 5-Phospho Erythronohydroxamic Acid, A New Class of Potent Trypanocidal Compounds [PDF]
, 2010 RNAi and enzymatic studies have shown the importance of 6-phosphogluconate dehydrogenase (6-PGDH) in Trypanosoma brucei for the parasite survival and make it an attractive drug target for the development of new treatments against human African ...
Alibu, Vincent P. +6 more
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Conflict and Emerging Infectious Diseases [PDF]
, 2007 Public health interventions and surveillance and response systems can contribute to disease ...
Agutu +31 more
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Nuevas tecnologías de la información y comunicación al servicio de la enfermería (Tablet, móviles, etc.) [PDF]
, 2015 En este proyecto se pretende crear una aplicación de salud relacionada con las enfermedades infecciosas, por la incidencia de estas en viajeros a los trópicos y su carácter prevenible.
Díez Fadrique, Galadrie Sofía
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Monovinyl sulfone beta-cyclodextrin. A flexible drug carrier system [PDF]
, 2014 Cyclodextrins have been conjugated to target various receptors and have also been functionalized with carbohydrates for targeting specific organs. However, this approach is based on a rigid design that implies the ad hoc synthesis of each cyclodextrin ...
del Castillo, T +5 more
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Computer-aided identification of Trypanosoma brucei uridine diphosphate galactose 4'-epimerase inhibitors : toward the development of novel therapies for African sleeping sickness [PDF]
, 2010 Trypanosoma brucei, the causative agent of human African trypanosomiasis, affects tens of thousands of sub-Saharan Africans. As current therapeutics are inadequate due to toxic side effects, drug resistance, and limited effectiveness, novel therapies are
Gehrig S. +56 more
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